To return to FlyBase, see FlyBase Gene Report: Dmel\TfIIB.
|Name||Transcription factor IIB|
The gene Transcription factor IIB is referred to in FlyBase by the symbol Dmel\TfIIB (CG5193, FBgn0004915). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: transcription factor binding. There is experimental evidence that it is involved in the biological process: transcriptional start site selection at RNA polymerase II promoter; regulation of DNA binding; regulation of transcription from RNA polymerase II promoter. 37 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cyclin-like; Transcription factor TFIIB; Transcription factor TFIIB, conserved site; Transcription factor TFIIB, cyclin-like domain; Zinc finger, TFIIB-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634172_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of TfIIB. Gene sequence location is 2L:10431338..10433116.