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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\TfIIB.

Symbol Dmel\TfIIB
Name Transcription factor IIB
Species Drosophila melanogaster
Annotation symbol CG5193
FlyBase ID FBgn0004915

The gene Transcription factor IIB is referred to in FlyBase by the symbol Dmel\TfIIB (CG5193, FBgn0004915). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: transcription factor binding. There is experimental evidence that it is involved in the biological process: transcriptional start site selection at RNA polymerase II promoter; regulation of DNA binding; regulation of transcription from RNA polymerase II promoter. 37 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cyclin-like; Transcription factor TFIIB; Transcription factor TFIIB, conserved site; Transcription factor TFIIB, cyclin-like domain; Zinc finger, TFIIB-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634172_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of TfIIB. Gene sequence location is 2L:10431338..10433116.


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