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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\Toll-7.

Symbol Dmel\Toll-7
Name Toll-7
Species Drosophila melanogaster
Annotation symbol CG8595
FlyBase ID FBgn0034476

The gene Toll-7 is referred to in FlyBase by the symbol Dmel\Toll-7 (CG8595, FBgn0034476). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: virion binding. There is experimental evidence that it is involved in the biological process: positive regulation of autophagy; defense response to virus. 9 alleles are reported. The phenotypes of these alleles are annotated with: leg; eye; wing disc; adult abdomen; wing; ventral thoracic disc; wing vein. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat, typical subtype; Leucine-rich repeat-containing N-terminal; Toll/interleukin-1 receptor homology (TIR) domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1639160_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Toll-7. Gene sequence location is 2R:15714410..15720473.


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