To return to FlyBase, see FlyBase Gene Report: Dmel\Traf4.
|Name||TNF-receptor-associated factor 4|
The gene TNF-receptor-associated factor 4 is referred to in FlyBase by the symbol Dmel\Traf4 (CG3048, FBgn0026319). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 13 unique biological process terms, many of which group under: single-organism developmental process; cellular component organization or biogenesis; biological regulation; programmed cell death; localization; gland morphogenesis; post-embryonic organ morphogenesis; sensory organ development; instar larval development; cellular component movement; positive regulation of MAPK cascade; regulation of apoptotic process; cell fate commitment; cell junction organization. 17 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; eye photoreceptor cell; imaginal disc; ommatidium; ventral furrow. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: MATH; SIAH-type domain; TNF receptor-associated factor TRAF; TRAF-like; Zinc finger, TRAF-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult heart. Gene sequence location is 2L:4361925..4380716.