To return to FlyBase, see FlyBase Gene Report: Dmel\Upf2.
The gene Upf2 is referred to in FlyBase by the symbol Dmel\Upf2 (CG2253, FBgn0029992). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: RNA binding; DNA binding. There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; synapse organization. 23 alleles are reported. The phenotype of these alleles is annotated with: dorsal appendage. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-type fold; MIF4-like, type 1/2/3; MIF4G-like, type 3; Up-frameshift suppressor 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1631256_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Upf2. Gene sequence location is X:7964277..7969499.