To return to FlyBase, see FlyBase Gene Report: Dmel\Vha100-5.
|Name||Vacuolar H<up>+</up> ATPase 100kD subunit 5|
The gene Vacuolar H+ ATPase 100kD subunit 5 is referred to in FlyBase by the symbol Dmel\Vha100-5 (CG12602, FBgn0032373). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: proton-transporting ATPase activity, rotational mechanism. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ATP hydrolysis coupled proton transport. 6 alleles are reported. The phenotype of these alleles is annotated with: wing. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ATPase, V0 complex, subunit 116kDa; ATPase, V0 complex, subunit 116kDa, eukaryotic. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval hindgut, larval Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult hindgut, adult Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1636474_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG12602. Gene sequence location is 2L:11738948..11744524.