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This gene article is a stub. It has been seeded with the automatically generated summary from FlyBase release FB2013_02. Please help improve this summary by logging in and editing it.

To return to FlyBase, see FlyBase Gene Report: Dmel\blow.

Symbol Dmel\blow
Name blown fuse
Species Drosophila melanogaster
Annotation symbol CG1363
FlyBase ID FBgn0004133

The gene blown fuse is referred to in FlyBase by the symbol Dmel\blow (CG1363, FBgn0004133). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: phospholipid binding. There is experimental evidence that it is involved in the biological process: myoblast fusion; actin cytoskeleton organization; mesoderm development. 13 alleles are reported. The phenotypes of these alleles are annotated with: myoblast; presumptive embryonic/larval muscle system; embryonic myoblast; somatic muscle primordium; fusion competent cell; A1-7 dorsal acute muscle 1; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Pleckstrin homology domain; Pleckstrin homology-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval/adult hindgut, adult salivary gland, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1623594_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of blow. Gene sequence location is 2R:3467993..3474584.


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