To return to FlyBase, see FlyBase Gene Report: Dmel\blow.
The gene blown fuse is referred to in FlyBase by the symbol Dmel\blow (CG1363, FBgn0004133). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: phospholipid binding. There is experimental evidence that it is involved in the biological process: myoblast fusion; actin cytoskeleton organization; mesoderm development. 13 alleles are reported. The phenotypes of these alleles are annotated with: myoblast; presumptive embryonic/larval muscle system; embryonic myoblast; somatic muscle primordium; fusion competent cell; A1-7 dorsal acute muscle 1; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Pleckstrin homology domain; Pleckstrin homology-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval/adult hindgut, adult salivary gland, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1623594_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of blow. Gene sequence location is 2R:3467993..3474584.