FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term type II hypersensitivity ID (Ontology) GO:0002445 (Gene Ontology)
Definition An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.[ ISBN:0781735149 ]
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acute inflammatory response to antigenic stimulus
 |__hypersensitivity_________________________
leukocyte mediated immunity                  |
 |__myeloid leukocyte mediated immunity______|
B cell mediated immunity                     |
 |__immunoglobulin mediated immune response__|
                                             type II hypersensitivity
                                              |__regulation of type II hypersensitivity
                                              |   |__negative regulation of type II hypersensitivity(+)
                                              |   |__positive regulation of type II hypersensitivity(+)
                                              |   |__regulation of type IIa hypersensitivity(+)
                                              |   |__regulation of type IIb hypersensitivity(+)
                                              |__type IIa hypersensitivity
                                              |   |__antibody-dependent cellular cytotoxicity(+)
                                              |   |__regulation of type IIa hypersensitivity(+)
                                              |__type IIb hypersensitivity
                                                  |__regulation of type IIb hypersensitivity(+)
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Is a myeloid leukocyte mediated immunity
hypersensitivity
immunoglobulin mediated immune response
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Wikipedia:Type_II_hypersensitivity