General Information
Term	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	ID (Ontology)	GO:0002460 (Gene Ontology)
Definition	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.[ ISBN:0781735149 ISBN:1405196831 ]
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General Information

Term

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

ID (Ontology)

GO:0002460 (Gene Ontology)

Definition

An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.[ ISBN:0781735149 ISBN:1405196831 ]

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QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

  immune response
   |__adaptive immune response
       |__adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
           |__adaptive immune effector response involving T cells and B lineage cells
           |__adaptive immune memory response involving T cells and B cells
           |__B cell mediated immunity
           |   |__B cell antigen processing and presentation(+)
           |   |__B cell cytokine production(+)
           |   |__immunoglobulin mediated immune response(+)
           |   |__peripheral B cell tolerance induction(+)
           |   |__regulation of B cell mediated immunity(+)
           |__germinal center formation
           |   |__regulation of germinal center formation(+)
           |__primary adaptive immune response involving T cells and B cells
           |__regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
           |   |__negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(+)
           |   |__positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(+)
           |   |__regulation of B cell mediated immunity(+)
           |   |__regulation of germinal center formation(+)
           |   |__regulation of T cell mediated immunity(+)
           |   |__regulation of T-helper 1 type immune response(+)
           |   |__regulation of T-helper 17 type immune response(+)
           |   |__regulation of tolerance induction dependent upon immune response(+)
           |__T cell mediated immunity
           |   |__peripheral T cell tolerance induction(+)
           |   |__regulation of T cell mediated immunity(+)
           |   |__T cell antigen processing and presentation(+)
           |   |__T cell cytokine production(+)
           |   |__T cell mediated cytotoxicity(+)
           |   |__T cell mediated immune response to tumor cell(+)
           |   |__type IV hypersensitivity(+)
           |__T-helper 1 type immune response
           |   |__regulation of T-helper 1 type immune response(+)
           |   |__T-helper 1 cell cytokine production(+)
           |   |__T-helper 1 cell differentiation(+)
           |__T-helper 17 type immune response
           |   |__regulation of T-helper 17 type immune response(+)
           |   |__T-helper 17 cell differentiation(+)
           |__tolerance induction dependent upon immune response
               |__peripheral tolerance induction(+)
               |__regulation of tolerance induction dependent upon immune response(+)
               |__tolerance induction to nonself antigen(+)

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