FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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Term negative regulation of immune system process ID (Ontology) GO:0002683 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
Also Known As "down regulation of immune system process" ; "down-regulation of immune system process" ; "downregulation of immune system process"
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immune system process
 |__regulation of immune system process________
regulation of biological process               |
 |__regulation of immune system process________|
 |__negative regulation of biological process__|
                                               negative regulation of immune system process  117 rec.
                                                |__negative regulation of activated T cell autonomous cell death
                                                |__negative regulation of activation-induced cell death of T cells
                                                |__negative regulation of antigen processing and presentation
                                                |   |__negative regulation of antigen processing and presentation of peptide antigen(+)
                                                |   |__negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(+)
                                                |   |__negative regulation of antigen processing and presentation via MHC class Ib(+)
                                                |   |__negative regulation of B cell antigen processing and presentation
                                                |   |__negative regulation of dendritic cell antigen processing and presentation(+)
                                                |   |__negative regulation of macrophage antigen processing and presentation
                                                |   |__negative regulation of monocyte antigen processing and presentation
                                                |   |__negative regulation of non-professional antigen presenting cell antigen processing and presentation
                                                |   |__negative regulation of T cell antigen processing and presentation
                                                |__negative regulation of antigen receptor-mediated signaling pathway
                                                |   |__negative regulation of B cell receptor signaling pathway
                                                |   |__negative regulation of T cell receptor signaling pathway(+)
                                                |__negative regulation of cytoplasmic pattern recognition receptor signaling pathway
                                                |   |__negative regulation of cGAS/STING signaling pathway
                                                |   |__negative regulation of inflammasome-mediated signaling pathway(+)
                                                |   |__negative regulation of MDA-5 signaling pathway
                                                |   |__negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(+)
                                                |   |__negative regulation of RIG-I signaling pathway
                                                |   |__negative regulation of toll-like receptor 3 signaling pathway
                                                |   |__negative regulation of toll-like receptor 7 signaling pathway
                                                |   |__negative regulation of toll-like receptor 8 signaling pathway
                                                |   |__negative regulation of toll-like receptor 9 signaling pathway
                                                |   |__negative regulation of toll-like receptor 11 signaling pathway
                                                |   |__negative regulation of toll-like receptor 12 signaling pathway
                                                |   |__negative regulation of toll-like receptor 13 signaling pathway
                                                |__negative regulation of erythrocyte clearance
                                                |__negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
                                                |__negative regulation of hemocyte differentiation 19 rec.
                                                |   |__negative regulation of crystal cell differentiation 7 rec.
                                                |   |__negative regulation of lamellocyte differentiation 9 rec.
                                                |   |__negative regulation of plasmatocyte differentiation 3 rec.
                                                |__negative regulation of hemocyte proliferation 7 rec.
                                                |__negative regulation of hemopoiesis
                                                |   |__negative regulation of hematopoietic stem cell proliferation
                                                |   |__negative regulation of leukocyte differentiation(+)
                                                |__negative regulation of immune effector process 23 rec.
                                                |   |__negative regulation melanotic encapsulation of foreign target 3 rec.
                                                |   |__negative regulation of complement activation(+)
                                                |   |__negative regulation of granuloma formation
                                                |   |__negative regulation of leukocyte degranulation(+)
                                                |   |__negative regulation of leukocyte mediated immunity(+)
                                                |   |__negative regulation of mast cell activation involved in immune response
                                                |   |__negative regulation of memory T cell differentiation
                                                |   |__negative regulation of plasma cell differentiation
                                                |   |__negative regulation of production of molecular mediator of immune response(+) 20 rec.
                                                |   |__negative regulation of respiratory burst involved in inflammatory response
                                                |   |__negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
                                                |   |__negative regulation of T-helper 1 cell differentiation
                                                |   |__negative regulation of T-helper 2 cell differentiation
                                                |   |__negative regulation of T-helper 17 cell differentiation(+)
                                                |__negative regulation of immune response 66 rec.
                                                |   |__negative regulation of adaptive immune response(+)
                                                |   |__negative regulation of basophil degranulation
                                                |   |__negative regulation of eosinophil degranulation
                                                |   |__negative regulation of humoral immune response(+) 27 rec.
                                                |   |__negative regulation of immune response to tumor cell(+)
                                                |   |__negative regulation of inflammatory response to antigenic stimulus(+)
                                                |   |__negative regulation of innate immune response(+) 38 rec.
                                                |   |__negative regulation of mast cell activation involved in immune response
                                                |   |__negative regulation of memory T cell differentiation
                                                |   |__negative regulation of neutrophil degranulation
                                                |   |__negative regulation of plasma cell differentiation
                                                |   |__negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
                                                |   |__negative regulation of T-helper cell differentiation(+)
                                                |   |__negative regulation of type 2 immune response(+)
                                                |__negative regulation of leukocyte activation
                                                |   |__negative regulation of eosinophil activation
                                                |   |__negative regulation of lymphocyte activation(+)
                                                |   |__negative regulation of macrophage activation(+)
                                                |   |__negative regulation of mast cell activation(+)
                                                |   |__negative regulation of monocyte activation
                                                |   |__negative regulation of myeloid dendritic cell activation
                                                |   |__negative regulation of neutrophil activation
                                                |__negative regulation of leukocyte migration
                                                |   |__negative regulation of cellular extravasation(+)
                                                |   |__negative regulation of eosinophil migration(+)
                                                |   |__negative regulation of leukocyte chemotaxis(+)
                                                |   |__negative regulation of mononuclear cell migration(+)
                                                |   |__negative regulation of neutrophil migration(+)
                                                |__negative regulation of mast cell apoptotic process
                                                |__negative regulation of peptidoglycan recognition protein signaling pathway 47 rec.
                                                |__negative regulation of T cell costimulation
                                                |   |__negative regulation of CD4-positive, alpha-beta T cell costimulation
                                                |__negative regulation of tolerance induction
                                                |   |__negative regulation of B cell tolerance induction(+)
                                                |   |__negative regulation of central tolerance induction(+)
                                                |   |__negative regulation of lymphocyte anergy(+)
                                                |   |__negative regulation of natural killer cell tolerance induction
                                                |   |__negative regulation of T cell tolerance induction(+)
                                                |   |__negative regulation of tolerance induction dependent upon immune response(+)
                                                |   |__negative regulation of tolerance induction to self antigen
                                                |__negative regulation of toll-like receptor 1 signaling pathway
                                                |__negative regulation of toll-like receptor 2 signaling pathway
                                                |__negative regulation of toll-like receptor 4 signaling pathway
                                                |__negative regulation of toll-like receptor 5 signaling pathway
                                                |__negative regulation of toll-like receptor 6 signaling pathway
                                                |__negative regulation of toll-like receptor 10 signaling pathway
                                                |__negative regulation of toll-like receptor 15 signaling pathway
                                                |__negative regulation of toll-like receptor signaling pathway
                                                    |__negative regulation of MyD88-dependent toll-like receptor signaling pathway
                                                    |__negative regulation of MyD88-independent toll-like receptor signaling pathway
                                                    |__negative regulation of toll-like receptor 21 signaling pathway
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Is a regulation of immune system process
negative regulation of biological process
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Synonyms
  • "down regulation of immune system process" EXACT
    "down-regulation of immune system process" EXACT
    "downregulation of immune system process" EXACT
    "inhibition of immune system process" NARROW
Secondary IDs
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