FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term GO:0016832 ID (Ontology) GO:0016832 (Gene Ontology)
Definition Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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 Full annotation statements 
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 Gene Groups
 GO:0016832 (all annotations which use CV term, excluding "NOT" statements)       1
Spanning Tree (Parents/Children)
Only view relationship: 
GO:0016829
 |__GO:0016830__
                GO:0016832  7 rec.
                 |__GO:0004139 1 rec.
                 |__GO:0004150
                 |__GO:0004332 1 rec.
                 |__GO:0004793 1 rec.
                 |   |__GO:0008732 1 rec.
                 |__GO:0008117 1 rec.
                 |__GO:0008672
                 |__GO:0008674
                 |__GO:0008675
                 |__GO:0008738
                 |__GO:0008994
                 |__GO:0009025
                 |__GO:0018803
                 |__GO:0018813
                 |__GO:0033984
                 |__GO:0043801
                 |__GO:0043863
                 |__GO:0043876
                 |__GO:0046593
                 |__GO:0047438
                 |__GO:0047439
                 |__GO:0047440
                 |__GO:0047441
                 |__GO:0047606
                 |   |__GO:0052891
                 |   |__GO:0052892
                 |__GO:0047695
                 |__GO:0047864
                 |__GO:0047905
                 |__GO:0047906
                 |__GO:0050013
                 |__GO:0050014
                 |__GO:0050041
                 |__GO:0050179
                 |__GO:0050193
                 |__GO:0050217
                 |__GO:0050352
                 |__GO:0050419
                 |__GO:0050547
                 |__GO:0052919
                 |__GO:0061595
                 |__GO:0061609 1 rec.
                 |__GO:0061677
                 |__GO:0070497
                 |__GO:0097023
                 |__GO:0102083
                 |__GO:0103042
                 |__GO:0106099
                 |__GO:0106359 1 rec.
                 |   |__GO:0106376
                 |__GO:0120567 1 rec.
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Is a carbon-carbon lyase activity
Part of
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Synonyms
  • "aldolase activity" BROAD
Secondary IDs
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EC:4.1.2.-
Reactome:R-HSA-200651 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine"
Reactome:R-HSA-200735 "SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG"
Reactome:R-HSA-71249 "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly"