FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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Term DNA endonuclease activity, producing 5'-phosphomonoesters ID (Ontology) GO:0016888 (Gene Ontology)
Definition Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
Also Known As "endodeoxyribonuclease activity, producing 5' phosphomonoesters" ; "endodeoxyribonuclease activity, producing 5'-phosphomonoesters"
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endonuclease activity
 |__DNA endonuclease activity__________________
DNA nuclease activity                          |
 |__DNA endonuclease activity__________________|
hydrolase activity                             |
 |__hydrolase activity, acting on ester bonds__|
                                               DNA endonuclease activity, producing 5'-phosphomonoesters  13 rec.
                                                |__5'-flap endonuclease activity 6 rec.
                                                |__CC-preferring endodeoxyribonuclease activity
                                                |__class II DNA-(apurinic or apyrimidinic site) endonuclease activity 4 rec.
                                                |__deoxyribonuclease I activity 3 rec.
                                                |__deoxyribonuclease IV (phage-T4-induced) activity
                                                |__deoxyribonuclease V activity
                                                |__type I site-specific deoxyribonuclease activity
                                                |__type II site-specific deoxyribonuclease activity
                                                |__type III site-specific deoxyribonuclease activity
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Is a DNA endonuclease activity
hydrolase activity, acting on ester bonds
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Synonyms
  • "endodeoxyribonuclease activity, producing 5' phosphomonoesters" EXACT
    "endodeoxyribonuclease activity, producing 5'-phosphomonoesters" EXACT
Secondary IDs
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EC:3.1.21.-
Reactome:R-HSA-912368 "SPO11 hydrolyzes DNA forming double-strand breaks"