FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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Term leptin-mediated signaling pathway ID (Ontology) GO:0033210 (Gene Ontology)
Definition The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
Also Known As "leptin-mediated signalling pathway"
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cell surface receptor signaling pathway
 |__cytokine-mediated signaling pathway___
cellular response to hormone stimulus     |
 |__cellular response to leptin stimulus__|
response to leptin                        |
 |__cellular response to leptin stimulus__|
cellular response to cytokine stimulus    |
 |__cytokine-mediated signaling pathway___|
                                          leptin-mediated signaling pathway
                                           |__negative regulation of appetite by leptin-mediated signaling pathway
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Is a cytokine-mediated signaling pathway
Part of cellular response to leptin stimulus
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Synonyms
  • "adipocytokine signaling pathway" RELATED
    "leptin-mediated signalling pathway" EXACT
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