FB2026_03 , released September 17, 2026
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Term CD8-positive, alpha-beta T cell activation ID (Ontology) GO:0036037 (Gene Ontology)
Definition The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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  T cell activation
   |__alpha-beta T cell activation
       |__CD8-positive, alpha-beta T cell activation
           |__CD8-positive, alpha-beta T cell differentiation
           |   |__CD8-positive, alpha-beta cytotoxic T cell differentiation
           |   |__CD8-positive, alpha-beta intraepithelial T cell differentiation
           |   |__CD8-positive, alpha-beta regulatory T cell differentiation
           |   |__CD8-positive, alpha-beta T cell differentiation involved in immune response
           |   |__CD8-positive, alpha-beta T cell lineage commitment
           |   |__regulation of CD8-positive, alpha-beta T cell differentiation(+)
           |__CD8-positive, alpha-beta T cell proliferation
           |   |__activated CD8-positive, alpha-beta T cell proliferation
           |   |__regulation of CD8-positive, alpha-beta T cell proliferation(+)
           |__regulation of CD8-positive, alpha-beta T cell activation
               |__negative regulation of CD8-positive, alpha-beta T cell activation(+)
               |__positive regulation of CD8-positive, alpha-beta T cell activation(+)
               |__regulation of CD8-positive, alpha-beta T cell differentiation(+)
               |__regulation of CD8-positive, alpha-beta T cell proliferation(+)
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