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| Term | RIG-I signaling pathway | ID (Ontology) | GO:0039529 (Gene Ontology) |
| Definition | The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.[ PubMed:17328678 PubMed:19620789 PubMed:21435580 PubMed:25579795 ] | ||
| Also Known As | "DDX58 signaling pathway" ; "retinoic acid inducible gene I signaling pathway" ; "RIG-I signalling pathway" (for all, see Synonyms field below) | ||
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pattern recognition receptor signaling pathway__ intracellular receptor signaling pathway________| cytoplasmic pattern recognition receptor signaling pathway |__RIG-I signaling pathway |
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| Is a | cytoplasmic pattern recognition receptor signaling pathway | ||
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