FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity ID (Ontology) GO:0047323 (Gene Ontology)
Definition Catalysis of the reaction: ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = ADP + H+ + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase].
Also Known As "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity"
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  protein kinase activity
   |__protein serine/threonine kinase activity
       |__[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity
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Is a protein serine/threonine kinase activity
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Synonyms
  • "3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity" RELATED[ EC:2 ]
    "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity" EXACT
    "ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity" RELATED[ EC:2 ]
    "BCK" RELATED[ EC:2 ]
    "BCKD kinase activity" RELATED[ EC:2 ]
    "BCODH kinase activity" RELATED[ EC:2 ]
    "branched-chain 2-oxo acid dehydrogenase kinase activity" RELATED[ EC:2 ]
    "branched-chain alpha-ketoacid dehydrogenase kinase activity" RELATED[ EC:2 ]
    "branched-chain keto acid dehydrogenase kinase activity" RELATED[ EC:2 ]
    "branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity" RELATED[ EC:2 ]
    "STK2" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.11.4
MetaCyc:2.7.11.4-RXN
Reactome:R-HSA-5693148 "BCKDK phosphorylates BCKDH"
Reactome:R-HSA-9912480 "BCKDK loss-of-function mutations do not phosphorylate BCKDH"
RHEA:17301