FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term RNA destabilization ID (Ontology) GO:0050779 (Gene Ontology)
Definition Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 RNA destabilization (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | RNA destabilization       1
Spanning Tree (Parents/Children)
Only view relationship: 
RNA catabolic process
 |__regulation of RNA stability_________________________
positive regulation of metabolic process                |
 |__positive regulation of catabolic process____________|
regulation of catabolic process                         |
 |__positive regulation of catabolic process____________|
 |__regulation of RNA stability_________________________|
positive regulation of macromolecule metabolic process  |
 |__positive regulation of RNA metabolic process________|
post-transcriptional regulation of gene expression      |
 |__regulation of RNA stability_________________________|
regulation of RNA metabolic process                     |
 |__regulation of RNA stability_________________________|
 |__positive regulation of RNA metabolic process________|
regulation of biological quality                        |
 |__regulation of RNA stability_________________________|
                                                        RNA destabilization  71 rec.
                                                         |__mRNA destabilization 70 rec.
                                                         |   |__3'-UTR-mediated mRNA destabilization 5 rec.
                                                         |   |__miRNA-mediated gene silencing by mRNA destabilization 26 rec.
                                                         |   |__nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(+) 26 rec.
                                                         |   |__piRNA-mediated gene silencing by mRNA destabilization(+) 12 rec.
                                                         |   |__polyadenylation-dependent mRNA catabolic process(+)
                                                         |   |__polyuridylation-dependent mRNA catabolic process(+) 2 rec.
                                                         |   |__siRNA-mediated gene silencing by mRNA destabilization(+) 1 rec.
                                                         |   |__transposable element silencing by mRNA destabilization(+) 10 rec.
                                                         |__tRNA destabilization
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a positive regulation of catabolic process
regulation of RNA stability
positive regulation of RNA metabolic process
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts