FB2026_03 , released September 17, 2026
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Term type I interferon-mediated signaling pathway ID (Ontology) GO:0060337 (Gene Ontology)
Definition The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.[ PubMed:32464097 ]
Also Known As"type I interferon signaling pathway" ; "type I interferon-activated signaling pathway"
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cytokine-mediated signaling pathway
 |__interferon-mediated signaling pathway___
response to type I interferon               |
 |__cellular response to type I interferon__|
cellular response to cytokine stimulus      |
 |__cellular response to type I interferon__|
                                            type I interferon-mediated signaling pathway
                                             |__regulation of type I interferon-mediated signaling pathway
                                                 |__negative regulation of type I interferon-mediated signaling pathway
                                                 |__positive regulation of type I interferon-mediated signaling pathway
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Is a interferon-mediated signaling pathway
Part of cellular response to type I interferon
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Synonyms
  • "type I interferon signaling pathway" EXACT
    "type I interferon-activated signaling pathway" EXACT
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Reactome:R-HSA-909733 "Interferon alpha/beta signaling"