FB2026_03 , released September 17, 2026
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Term inflammasome-mediated signaling pathway ID (Ontology) GO:0141084 (Gene Ontology)
Definition An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis.[ PubMed:35883561 ]
Also Known As"inflammasome-mediated signal transduction"
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pattern recognition receptor signaling pathway__
intracellular receptor signaling pathway________|
                                                cytoplasmic pattern recognition receptor signaling pathway
                                                 |__inflammasome-mediated signaling pathway
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Is a cytoplasmic pattern recognition receptor signaling pathway
Part of inflammatory response
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