FB2026_03 , released September 17, 2026
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Term IscS-TusA complex ID (Ontology) GO:1990329 (Gene Ontology)
Definition A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.[ PubMed:20404999 ]
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  sulfurtransferase complex
   |__L-cysteine desulfurase complex
       |__IscS-TusA complex
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