FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

cosedimentation through density gradient

ID (Ontology)

MI:0029 (Molecular Interactions)

Definition

Sedimentation through a density gradient measures the sedimentation rate of a mixture of proteins through either a glycerol or sucrose gradient. Two interacting proteins will sediment mostly as a complex at concentrations above the binding constant. By varying the concentration of one or both of the complex constituents and taking into account the dilution of the species during sedimentation, one can reasonably accurately estimate the binding constant.[ PubMed:10410796 ]

Also Known As

"density sedimentatio"

Comment

Links to External Ontologies

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Interaction Groups
cosedimentation through density gradient (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

  biochemical
   |__cosedimentation
       |__cosedimentation through density gradient  95 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cosedimentation
Part of
Synonyms & Secondary IDs
Synonyms
	"density sedimentatio" EXACT PSI-MI-short
Secondary IDs

External Crossreferences & Linkouts