FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term voltage-gated sodium channel activity ID (Ontology) GO:0005248 (Gene Ontology)
Definition Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.[ ISBN:0815340729 ]
Also Known As "voltage gated sodium channel activity" ; "voltage-dependent sodium channel activity" ; "voltage-gated sodium ion channel activity" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 voltage-gated sodium channel activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | voltage-gated sodium channel activity       --       4
Spanning Tree (Parents/Children)
Only view relationship: 
monoatomic cation channel activity_____________
sodium ion transmembrane transporter activity__|
                                               sodium channel activity
                                                |__voltage-gated sodium channel activity  5 rec.
                                                    |__mechanosensitive voltage-gated sodium channel activity
                                                    |__voltage-gated sodium channel activity involved in cardiac muscle cell action potential
                                                        |__voltage-gated sodium channel activity involved in AV node cell action potential
                                                        |__voltage-gated sodium channel activity involved in bundle of His cell action potential
                                                        |__voltage-gated sodium channel activity involved in Purkinje myocyte action potential
                                                        |__voltage-gated sodium channel activity involved in SA node cell action potential
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Is a sodium channel activity
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Synonyms
  • "voltage gated sodium channel activity" EXACT
    "voltage-dependent sodium channel activity" EXACT
    "voltage-gated sodium ion channel activity" EXACT
    "voltage-sensitive sodium channel" EXACT
Secondary IDs
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Reactome:R-HSA-5576895 "SCNAs:SNCBs transport Na+ from extracellular region to cytosol"