FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term sodium channel activity ID (Ontology) GO:0005272 (Gene Ontology)
Definition Enables the energy-independent facilitated diffusion of a sodium ion through a transmembrane aqueous pore or channel.[ ISBN:0815340729 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      33
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 Gene Groups Genes
 sodium channel activity (all annotations which use CV term, excluding "NOT" statements)       3     33
     enables | sodium channel activity       --      33
Spanning Tree (Parents/Children)
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monoatomic ion channel activity
 |__monoatomic cation channel activity________________
monoatomic cation transmembrane transporter activity  |
 |__monoatomic cation channel activity________________|
metal ion transmembrane transporter activity          |
 |__sodium ion transmembrane transporter activity_____|
                                                      sodium channel activity  50 rec.
                                                       |__bile acid-gated sodium channel activity
                                                       |__ligand-gated sodium channel activity 41 rec.
                                                       |   |__kainate selective glutamate receptor activity 9 rec.
                                                       |   |__pH-gated sodium channel activity 1 rec.
                                                       |__voltage-gated sodium channel activity 5 rec.
                                                           |__mechanosensitive voltage-gated sodium channel activity
                                                           |__voltage-gated sodium channel activity involved in cardiac muscle cell action potential(+)
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Is a monoatomic cation channel activity
sodium ion transmembrane transporter activity
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Synonyms
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Reactome:R-HSA-2730664 "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol"
Reactome:R-HSA-3295580 "TRPM4,5 transport extracellular Na+ to cytosol"
Reactome:R-HSA-9717374 "SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol"
Reactome:R-HSA-9717382 "SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol"
Reactome:R-HSA-9717395 "TRPM5 transports Na+ from the extracellular region to the cytosol"
Reactome:R-HSA-9717396 "SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol"