paired type homeobox genes. - Noll, M. (1998)
>Hi Marcus, > >FlyBase has been going back in time, over some older publications, >gathering some historic data for our genes files. In 1990 you published: >*x FBrf0051757 == Schneitz and Noll, 1990, Experientia 46(Abstr.): A82 > >in which you mentioned these paired type homeobox genes: >*a L13-4 >*a Pph13 >*a Pph25 > >My question is, have these been published since under different symbols? >If so we can amalgamate the information, and avoid having more FlyBase gene >records than there are genes. > >many thanks for your help, > >Rachel. > Dear Rachel, two of the three paired-type homeobox genes you mentioned are published: L13-4 is aristaless (al). The name L13-4 should actually be lambda13-4, which is the name of the genomic phage covering aristaless, as shown in our publication by Schneitz et al., Genes & Dev. 7, 114-129 (1993). The GenBank accession number of the published sequence is L08401. PPH25 is the same as D-goosecoid (D-gsc) and has been published by Hahn and Jaeckle, EMBO J. 15, 3077-3084 (1996). Its GenBank accession number is U52968. Our unpublished work locates this gene to chromosomal band 21D1,2 and orients it on the chromosome such that the direction of its transcription is oriented towards the telomere. PPH13 is still unpublished until someone will publish it for us! It is located immediately distal to PPH25 (in the neighbouring RI-fragment), i.e. D-gsc, and its transcription occurs in the opposite orientation to that of D-gsc, i.e. the 3' ends of D-gsc and PPH13 are oriented towards each other. The homeodomain of PPH13 is also of the paired-type. I hope this clarifies matters somewhat. With best regards, Markus