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General Information
Symbol
Df(3R)hhE23
Species
D. melanogaster
Name
FlyBase ID
FBab0000010
Feature type
Also Known As
hhE23
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << hh << bk2 << klg

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (citation unavailable) Left limit of break 2 from inclusion of hh (FBrf0067338) Right limit of break 2 from non-inclusion of klg (FBrf0067338)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Heterozygosity for Df(3R)hhE23 results in 0.2% X chromosome nondisjunction and 1.6% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    The right and left hemispheres of the brain are joined at the midline in the b1 region or separated by an abnormally small space (because of excess cells in this region) in 70% of mutant embryos. The preoral brain commissure shows abnormal defasciculation. The frontal commissure is missing and there is a significant decrease in the area occupied by neuronal nuclei and in the number of glia in the b1 region. In the b2-S3 region of the brain, the longitudinal connectives are disrupted, and the area occupied by the neuronal nuclei and the number of glia are reduced. There is a decrease in the number of apoptotic cells at the dorsal midline of the brain in late stage 13 mutant embryos. The number of brain ganglionic mother cells in stage 11 mutant embryos is decreased compared to wild type.

    Shows no maternal enhancement of dpphr4.

    Stocks (0)
    Notes on Origin
    Discoverer

    Joan Hooper.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (5)
    Reported As
    Name Synonyms
    hedgehogE23
    Secondary FlyBase IDs
    • FBal0031484
    References (11)