FlyBase Aberration Report: Dmel\Df(1)HF368

General Information

Symbol

Df(1)HF368

Species

D. melanogaster

Name

FlyBase ID

FBab0000429

Feature type

chromosomal_deletion

Computed Breakpoints include

11A2;11B9

Features within 11A2--11B9

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Eeken and Sobels, 1990)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Konrad et al., 1998, Smith et al., 1996, Pauli et al., 1995, Eeken and Sobels, 1990, Craymer and Roy, 1980)

Breakpoints

11A2;11B9

(Pauli et al., 1995, Craymer and Roy, 1980)

11A2;11B

(Eeken and Sobels, 1990)

11A2;[]

(Smith et al., 1996)

11A2-11A3;11B9

(Konrad et al., 1998)

Causes alleles

cac^HF368

(Smith et al., 1996)

Carries alleles

Transposon Insertions

Formalized genetic data

cac << bk1 << l(1)11Ad << Lsp1α << bk2

Genetic mapping information

Comments

Breaks within protein coding region and deletes the 5' (proximal) portion of the gene.

(Smith et al., 1996)

Comments on Cytology

Deletion of 18/22 bands.

(Eeken and Sobels, 1990)

Left limit of break 1 from polytene analysis (FBrf0034402) Right limit of break 1 from inclusion of gd (FBrf0102954) Limits of break 2 from polytene analysis (FBrf0034402)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Ten-a

(Rakovitsky et al., 2007)

tsg

(Rakovitsky et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

hop

(Eeken et al., 1985)

l(1)10Ae

(Eeken et al., 1985)

l(1)10Cc

(Eeken et al., 1985)

l(1)10Fg

(Eeken et al., 1985)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken et al., 1985)

l(1)ESHS41

(Eeken et al., 1985)

l(1)ESHS42

(Eeken et al., 1985)

l(1)ESHS43

(Eeken et al., 1985)

l(1)ESHS44

(Eeken et al., 1985)

l(1)ESHS45

(Eeken et al., 1985)

Polr2A

(Eeken et al., 1985)

ras

(Eeken et al., 1985)

rtv

(Eeken et al., 1985)

sbr

(Eeken et al., 1985)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Df(1)HF368 hemizygous embryos exhibit head and thorax defects similar to tsg loss of function mutants.

With a very low penetrance, Df(1)HF368 hemizygous embryos show subtle defects in segmentation, including partial fusion of denticle band pairs in the register seen for Ten-m mutants.

(Rakovitsky et al., 2007)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Heterozygous females exhibit reduced viability and fertility.

(Eeken and Sobels, 1990)

Stocks (2)

Bloomington

965

Df(1)HF368, cac^HF368/FM7c

Kyoto

106146

Df(1)HF368, cac^HF368/FM7c

Notes on Origin

Discoverer

Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df (1)HF368

(Rakovitsky et al., 2007)

Df(1)HF368

(Rakovitsky et al., 2007, Savvateeva-Popova et al., 2004, Hirose et al., 2001)

Df(1)Hf368

(Ray and Dowse, 2005)

Df(1)fw-HF368

HF368

(Sanchez et al., 1994)

LIMK1^Df(1)HF368

(Miller et al., 2011)

Name Synonyms

Secondary FlyBase IDs

References (26)

Report Sections

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