FlyBase Aberration Report: Dmel\Df(1)N19

General Information

Symbol

Df(1)N19

Species

D. melanogaster

Name

FlyBase ID

FBab0000596

Feature type

chromosomal_deletion

Also Known As

N19

Computed Breakpoints include

17A1;18A2

Features within 17A1--18A2

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Eberl et al., 1992)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Cook et al., 1997, Duffy et al., 1996, Fradkin et al., 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Landecker et al., 1994, Ferrus et al., 1990, Deak et al., 1982, Craymer and Roy, 1980)

Breakpoints

17A;18A2

(Deak et al., 1982, Craymer and Roy, 1980)

17A7-17A8;18A6-18A7

(Ferrus et al., 1990)

16F;19B

(Eisenberg et al., 1992)

17A1;18A2

(Cook et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Landecker et al., 1994)

17A3-17A6;17F2-18A3

(Fradkin et al., 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

wupA << bk1 << fliH << bk2

Genetic mapping information

Comments

Comments on Cytology

Ref: Craymer and Roy, 1980, D. I. S. 55: 200--204.

(Fradkin et al., 1995)

First chromosome breakpoint is 20kb distal to the first chromosome breakpoint of T(1;Y)B137.

(Ferrus et al., 1990)

Limits of break 1 from polytene analysis (FBrf0076124) Limits of break 2 from polytene analysis (FBrf0034402)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

fout

(Phillis et al., 1993)

upd1

(Craymer and Roy, 1980)

usdy

(Phillis et al., 1993)

wupA

(Firdaus et al., 2015, Homyk and Emerson, 1988)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)N19 weakly decreases transmission.

(Cook et al., 1997)

Df(1)svr/Df(1)N19 and Df(1)N71/Df(1)N19 double heterozygous females have reduced viability; only 30% and 8% respectively survive compared to control flies. Viability is recovered if the Df(1)svr/Df(1)N19 or Df(1)N71/Df(1)N19 females also carry Sxl^M1.

(Sanchez et al., 1994)

NOT in combination with other aberrations

29% of Df(1)N19 homozygous embryos show defects in germ-band extension.

(Bertet et al., 2009)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22.

(Burnette et al., 1999)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Homozygous embryos are very abnormal compared to wild-type.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxl^f1. Female lethality is also reduced when in combination with da¹ but restored when in combination with emc^ML.

(Anand and Chandra, 1994)

'Sloppy' ventral cord.

(Smith et al., 1993)

Stocks (2)

970

106694

Notes on Origin

Discoverer

Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Df(1)970

(Ligoxygakis et al., 2002)

Df(1)N19

(Ripp et al., 2018, Firdaus et al., 2015, Ren et al., 2014, Becalska and Gavis, 2010, Wang et al., 2008, Zenvirt et al., 2008, Crest et al., 2007, Phillis et al., 1993)

Df(970)

(Bertet et al., 2009)

Df970

(Mertens et al., 2005)

N19

(Sanchez et al., 1994, Mariol et al., 1987)

Name Synonyms

Secondary FlyBase IDs

References (49)

Report Sections

Open Close