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General Information
Symbol
Df(1)ct4b1
Species
D. melanogaster
Name
FlyBase ID
FBab0000798
Feature type
Also Known As
Df(1)ct4b1
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Carries alleles
Transposon Insertions
Formalized genetic data

l(1)ESHS31 << bk1 << l(1)47 << dec-1 << bk2 << l(1)ESHS35

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

Proximal breakpoint lies between coordinates 3.6 and 4.0 on the molecular map of dec-1.

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0048669) Right limit of break 1 from polytene analysis (FBrf0053739) Limits of break 2 from polytene analysis (FBrf0025084)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Df(1)R19/Df(1)ct4b1 females have good viability, about 20% have a kinked femur-like phenotype.

    Df(1)ct4b1/Dp(1;3)sn13a1 viable (Lefevre and Johnson, 1973, Genetics 74:633-45 ).

    NOT in combination with other aberrations

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 10-24%.

    Shows no maternal enhancement of dpphr4.

    Midgut development of mutant embryos is wild type.

    Salivary ducts are absent in homozygous embryos. Malpighian tubule material is not elongated.

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Embryos hemizygous for Df(1)ct-J4 and Df(1)ct4b1 were examined with polarised light microscopy and antibody staining: muscle pattern incomplete due to muscle absences.

    Homozygous embryos lack Malpighian tubules and the gut wall is 3--4 fold thicker than wild type at the junction of the posterior and anterior midgut.

    Homozygous lethal.

    Stocks (4)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (7)
    References (47)