FB2026_03 , released September 17, 2026
Aberration: Dmel\Df(1)rst2
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General Information
Symbol
Df(1)rst2
Species
D. melanogaster
Name
Deficiency (1) roughest
FlyBase ID
FBab0000919
Feature type
chromosomal_deletion
Also Known As
Df(1)rst2, rst2
Computed Cytological Breakpoints (relative to progenitor)

3C3;3C6

Features within 3C3--3C6
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
(Lefevre and Green, 1972)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Judd, 1995, Smolik-Utlaut and Gelbart, 1987, Welshons and Welshons, 1986, Gubb et al., 1985, Gubb et al., 1984, Lefevre and Green, 1972)
Cytological Breakpoints (relative to progenitor)

3C3;3C5-3C6

(Lefevre and Green, 1972)

3C3-3C4;3C6-3C7

(Judd, 1995, Smolik-Utlaut and Gelbart, 1987, Gubb et al., 1985, Gubb et al., 1984)

3C3;3C5

(Welshons and Welshons, 1986)

3C5;3C7

(Wolff and Ready, 1991)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << rst << vt << bk2

Genetic mapping information
Comments
Comments on Cytology

Ref: FBrf0023492.

(Welshons and Welshons, 1986)

Limits of break 1 from polytene analysis (FBrf0023492) Left limit of break 2 from polytene analysis (FBrf0040529) Right limit of break 2 from polytene analysis (FBrf0023492)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
rst
(Ruiz-Gomez et al., 2000, Judd, 1995, Smolik-Utlaut and Gelbart, 1987, Lefevre and Green, 1972)
vt
(Ruiz-Gomez et al., 2000, Judd, 1995, Lefevre and Green, 1972)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Viable in combination with Df(1)w67k30.

    (Ruiz-Gomez et al., 2000, Lefevre, 1970)

    The semilethality of the Df(1)rst2 chromosome is covered by Tp(1;2)TE35B.

    (Gubb et al., 1985)
    NOT in combination with other aberrations

    Hemizygous males and homozygous females are viable and fertile though emergence is delayed. z1 Df(1)rst2 males are rough-eyed with wild type eye colour. Homozygous females are rough-eyed with z eye colour.

    (Judd, 1995)

    Rough eyes and irregular optic chiasms.

    (Ramos et al., 1993)

    Semilethal.

    (Gubb et al., 1985)

    Timing of adult emergence is delayed.

    (Lefevre and Green, 1972)

    hemizygous male viable homozygous female viable hemizygous and homozygous emergence delayed (Lefevre and Green, 1972, Chromosoma 36: 391-412).

    Stocks (2)
    Notes on Origin
    Discoverer

    Bridges, 7th April 1933.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Interacts with Nfa-swb to suppress eye roughening.

    (Wolff and Ready, 1991)
    Synonyms and Secondary IDs (5)
    References (18)