FlyBase Aberration Report: Dmel\Df(1)y74k24.1

General Information

Symbol

Df(1)y74k24.1

Species

D. melanogaster

Name

FlyBase ID

FBab0001099

Feature type

chromosomal_deletion

Also Known As

Df(1)y^74k24.1

Computed Breakpoints include

1A1;1B13

Features within 1A1--1B13

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

spontaneous

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Duffy et al., 1996, Voelker et al., 1989, Craymer and Roy, 1980)

Breakpoints

1A1;1B9-1B10

(Voelker et al., 1989, Craymer and Roy, 1980)

1A1;1B5-1B10

(Duffy et al., 1996)

Causes alleles

RpL36^y74k24.1

(Duffy et al., 1996)

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << l(1)1Aj << RpL36 << bk2 << su(s)

Genetic mapping information

Comments

Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0034402) Left limit of break 2 from inclusion of l(1)1Bi (FBrf0049919) Right limit of break 2 from non-inclusion of su(s) (FBrf0049919)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Kramers et al., 1991, Kramers et al., 1983, Craymer and Roy, 1980)

cin

(Kramers et al., 1991, Kramers et al., 1983)

elav

(Kramers et al., 1991, Kramers et al., 1983)

ewg

(Kramers et al., 1991, Kramers et al., 1983)

l(1)1Ac

(Kramers et al., 1991, Eeken et al., 1985, Kramers et al., 1983)

l(1)1Ad

(Kramers et al., 1991, Kramers et al., 1983)

l(1)1Ai

(Kramers et al., 1983)

l(1)1Aj

(Kramers et al., 1991)

l(1)1Bb

(Kramers et al., 1991, Kramers et al., 1983)

l(1)1Bc

(Kramers et al., 1991, Kramers et al., 1983)

l(1)1Bg

(Voelker et al., 1989)

l(1)1Bh

(Voelker et al., 1989)

Mybbp1A

(Duffy et al., 1996, Voelker et al., 1989)

pch

(Eeken et al., 1985)

RpL36

(Duffy et al., 1996)

(Kramers et al., 1991, Kramers et al., 1983, Craymer and Roy, 1980)

SkpA

(Khush et al., 2002)

svr

(Kramers et al., 1991, Kramers et al., 1983)

vnd

(Kramers et al., 1991, Kramers et al., 1983)

(Kramers et al., 1991, Kramers et al., 1983, Craymer and Roy, 1980)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Kramers et al., 1991, Eeken et al., 1985)

brc

(Kramers et al., 1991, Voelker et al., 1989, Kramers et al., 1983)

dor

(Kramers et al., 1991, Eeken et al., 1985)

fs(1)N

(Perez-Chiesa et al., 1983)

l(1)1Bk

(Voelker et al., 1989, Kramers et al., 1983)

l(1)1Ca

(Voelker et al., 1989)

l(1)1CDa

(Eeken et al., 1985)

l(1)1CDb

(Eeken et al., 1985)

l(1)1CDc

(Eeken et al., 1985)

l(1)1Da

(Voelker et al., 1989, Kramers et al., 1983)

l(1)1Ec

(Kramers et al., 1991, Eeken et al., 1985)

l(1)1Eg

(Kramers et al., 1991)

l(1)1Fc

(Kramers et al., 1991)

l(1)1Fg

(Kramers et al., 1991)

l(1)1Fh

(Kramers et al., 1991)

l(1)ESHS1

(Eeken et al., 1985)

l(1)ESHS3

(Eeken et al., 1985)

l(1)ESHS4

(Eeken et al., 1985)

l(1)ESHS6

(Eeken et al., 1985)

l(1)ESHS7

(Eeken et al., 1985)

l(1)ESHS8

(Eeken et al., 1985)

l(1)ESHS9

(Eeken et al., 1985)

l(1)ESHS10

(Eeken et al., 1985)

l(1)ESHS11

(Eeken et al., 1985)

mul

(Voelker et al., 1989, Eeken et al., 1985)

Mybbp1A

(Kramers et al., 1983)

RpL36

(Voelker et al., 1989)

su(sable)

(Voelker et al., 1989)

(Kramers et al., 1991, Voelker et al., 1989, Kramers et al., 1983)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Heterozygous Df(1)y74k24.1 mutant females exhibit a dilated cardiomyopathy phenotype, including an increased end-systolic dimension (EDD) and a decreased fractional shortening (FS) compared to controls. Bristles appear short and thin compared to wild type (Minute phenotype).

(Casad et al., 2011)

Acts as a dosage sensitive maternal modifier of run : causes tergite defects in greater than 65% of run³ heterozygotes. Shows a dominant Minute phenotype: short fine bristles, delayed development and reduced viability. Both phenotypes are alleviated by maternal P{1BD#1}.

(Duffy et al., 1996)

Stocks (2)

Bloomington

3922

C(1)DX, y¹ w¹ f¹/Df(1)y74k24.1, RpL36^y74k24.1/Dp(1;Y)y²61l

Kyoto

107269

C(1)DX, y¹ w¹ f¹/Df(1)y74k24.1, RpL36^y74k24.1/Dp(1;Y)y²*

Notes on Origin

Discoverer

Arose in: y² mutator stock of M.M. Green.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Df(1)74k24.1

(Khush et al., 2002)

Df(1)y74k24

(Duffy et al., 1996)

Df(1)y74k24.1

(Casad et al., 2011)

Df(1)y^-74k24.1

(Eeken et al., 1985)

Df(1)y^74k24.1

(Voelker et al., 1989, Wieschaus et al., 1984, Perez-Chiesa et al., 1983)

Dfy^74k24.1

(Kramers et al., 1991)

y^74k24.1

(Craymer and Roy, 1980)

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

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