FB2020_06, released Dec 22, 2020

Aberration: Dmel\Df(2L)Scorv18

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General Information
Symbol
Df(2L)Scorv18
Species
D. melanogaster
Name
Deficiency (2L) Scutoid
FlyBase ID
FBab0001549
Feature type
chromosomal_deletion
Also Known As
Df(2L)ScoR+18, ScoR+18
Computed Breakpoints include

35B1--2;35E1--F1;35D2--7;[<35D]

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Tp(2;2)Sco
(Roote et al., 1996, Ashburner et al., 1983, Ashburner et al., 1980)
Mutagen
X ray
(Ashburner et al., 1980)
Class of aberration (relative to wild type)
chromosomal_deletion
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ashburner et al., 1980)
Breakpoints

[];[]

(Ashburner et al., 1980)

35B1-35B2;35B2-35B4;35D1-35D2;35E2

(Ashraf et al., 1999)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << noc << Adh << bk2 << mol << wor << bk3 << sna << BicC << bk4

Genetic mapping information
Comments

FBrf0091058 and FBrf0082309 differ in their conclusions about molecular mapping of the proximal breakpoint of Df(2L)Scorv18 with respect to the BicC transcription unit. Weight of evidence favours the FBrf0091058 interpretation (see Roote, 1999.1.18, personal communication).

Comments on Cytology

Cytology like Tp(2;2)Sco.

(Roote et al., 1996)

Stated to break in BicC transcription unit.

(Mahone et al., 1995)

Cytologically similar to Tp(2;2)Sco.

(Ashburner et al., 1983)

Cytologically invisible deletion.

(Ashburner et al., 1980)

Left limit of break 1 from non-inclusion of elA (FBrf0039455) Right limit of break 1 from inclusion of Adh (FBrf0034393) Left limit of break 2 from inclusion of BicC (FBrf0051973) Right limit of break 2 from non-inclusion of Ca-α1D (FBrf0051973) Left limit of break 3 from complementation mapping against wor (citation unavailable) Right limit of break 3 from polytene analysis (citation unavailable) Right limit of break 4 from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    37% of ISNb nerves show a bypass phenotype in Df(2L)RM5/Df(2L)Scorv18 embryos (20% of ISNb nerves are wild type). 68% of ISNd nerves show a bypass phenotype in Df(2L)RM5/Df(2L)Scorv18 embryos (29% of ISNd nerves are wild type).

    (Pipes et al., 2001)

    In Df(2L)Scorv18/Df(2L)RM5 transheterozygotes (beat-Ia- BicC-) the SNb fails to diverge from the ISN completely (full bypass) in 68% segments or partially (partial bypass) in 28% segments.

    (Fambrough and Goodman, 1996)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer

    Ashburner.

     

    Revertant

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    (Roote et al., 1996)
    Synonyms and Secondary IDs (9)
    Reported As
    Symbol Synonym
    Df(2L)Sco18
    Df(2L)ScoR+18
    (Ashburner et al., 1980)
    Df(2L)ScoR+
    Df(2L)Scorv18
    Df(2L)ScoR+18
    (Pipes et al., 2001, Fambrough and Goodman, 1996, Mahone et al., 1995, Ashburner et al., 1990)
    Df(2L)Scorv18
    (Roote, 2002.1.15)
    Sco-rv18
    (Ashburner et al., 1999.10.12)
    ScoR+18
    (Ashburner and Harrington, 1984, Ashburner et al., 1983)
    Name Synonyms
    Deficiency (2L) Scutoid
    Secondary FlyBase IDs
      References (14)