37B9-37B10;37D1-37D2
37B9-37C1;37D1-37D2
37B9-37C2;37D1-37D2
l(2)37Bi << bk1 << hk << γTub37C << bk2 << l(2)37Da
This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).
Breakpoint(s) molecularly mapped
Deletes the entire 100 kb of DNA which carries Ddc and includes the coding region for the genes l(2)37Ba-brat (Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-94)
Df(2L)TW130/Df(2L)TW203 hk phenotype
Flies heterozygous for the deletion do not show a Minute bristle phenotype.
No corpus cardiacum defects are found in mutant embryos.
Homozygous dead embryos show a distribution of "double line" cuticle phenotype and ghost embryos indicative of mutation in serotinin biosynthesis/signalling.
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
The Df(2L)TW130 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.
Although l(2)37Ca1 and l(2)37Ca3 fail to complement Df(2L)TW130, l(2)37Ca2 is reported as complementing Df(2L)TW130. Although brat1 and brat2 fail to complement Df(2L)TW130, bratts1 is reported as complementing Df(2L)TW130.
Ref: FBrf0028752.
Left limit of break 1 from polytene analysis (FBrf0028752) Right limit of break 1 from inclusion of Catsup (FBrf0028753) Limits of break 2 from polytene analysis (FBrf0028752)