FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)prd1.7
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General Information
Symbol
Df(2L)prd1.7
Species
D. melanogaster
Name
FlyBase ID
FBab0001902
Feature type
chromosomal_deletion
Also Known As
Df(2L)prd1.7
Computed Breakpoints include

33B3;34A1-34A2

Features within 33B3--34A2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Verheyen et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Landecker et al., 1994)
Breakpoints

33B3-33B7;34A1-34A2

(Pauli et al., 1995, Schupbach and Wieschaus, 1989)

33B2-33B3;34A1-34A2

(Verheyen et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Landecker et al., 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

esc << bk1 << E(var)33AD << pdm2 << bk2

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Kilchherr et al., 1986, Frei et al., 1985, Frei et al., 1985)

Distal breakpoint mapped to the DNA (Frei et al., 1985).

Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Left limit of break 1 from polytene analysis (FBrf0049878) Right limit of break 1 from polytene analysis (FBrf0076124) Limits of break 2 from polytene analysis (FBrf0049878)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Df(2L)esc10 is semi-lethal in combination with Df(2L)prd1.7. Surviving males and females are fertile.

    (Levine et al., 2007)

    Df(2L)esc10/Df(2L)prd1.7 adult survivors lack almost all interommatidial bristles.

    (Hardiman et al., 2002)

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    Heterozygous Df(2L)prd1.7 larvae show a reduction in food ingestion rate of about 35% compared to wild-type larvae. Waste excretion rates of heterozygous Df(2L)prd1.7 larvae are reduced compared to wild type.

    (Gao et al., 2004)

    The Df(2L)prd1.7 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Df(2L)prd1.7 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces sterile male flies. These flies are female sterile.

    (Sawamura et al., 2000)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    100% of homozygotes lack cells from the RP2/sib lineage in all remaining hemisegments. Heterozygotes show a weak haploinsufficient phenotype, with approximately 6.5% of embryos having an RP2 lineage defect. All Df(2L)prd1.7/Df(2L)Prl embryos have hemisegments which show RP2/sib lineage defects.

    (Bhat et al., 1995)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos do not complete head involution and tracheae are disconnected. The midgut does not constrict and the midgut epithelium shows variable degrees of degeneration.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    eve-positive RP2/sib GMCs are not observed in 7.5hr deficiency embryos.

    (Bhat and Schedl, 1994)

    prd4/Df(2L)prd1.7 transheterozygotes only survive to adulthood in the presence of a copy of P{prd-SN20}. These adults give rise to fertile offspring.

    (Gutjahr et al., 1994)
    Stocks (3)
    Notes on Origin
    Discoverer

    Nusslein-Volhard.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (8)
    References (57)