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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)


Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Cdk5 << bk1 << Rho1 << Khc << bk2

Genetic mapping information
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0076476) Left limit of break 2 from inclusion of Khc (FBrf0053345)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Enhances the infantile phenotype of ApplUAS.cTa, Scer\GAL4Appl.G1a.

    NOT in combination with other aberrations

    Df(2R)Jp6 mutant embryos show normal cardiac cell alignment.

    The Df(2R)Jp6 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    Khc6/Df(2R)Jp6 larvae exhibit early loss of motor activity in the ventral posterior segments causing an inbalance in bodywall contractions such that larvae rhythmically flip their tails upward during locomotion. Mutation causes organelle-filled axonal swellings that exhibit abnormal accumulation of nerve terminal proteins, Syt1, Csp, Syx1A and Fas3. Slow axonal transport does not make a substantial contribution to the swellings. Mutation causes dystrophic neuromuscular junctions; the number of synaptic boutons per muscle 6/7 junction in segments A2 and A6 in wandering third instar larvae is reduced threefold and fivefold respectively. The terminal phenotype is completely rescued by a single copy of P{Khc7.5}.

    Stocks (2)
    Notes on Origin
    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments
    Synonyms and Secondary IDs (4)
    References (30)