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General Information
D. melanogaster
FlyBase ID
Feature type
Also Known As
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << mrn << bk2 << brm

Genetic mapping information
Comments on Cytology

All limits from polytene analysis (FBrf0098597)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Df(3L)BK10/Df(3L)ri-79c embryos show a failure to form a ventral furrow. The mesoderm primordium is internalised late.

    NOT in combination with other aberrations

    88% of mutant embryos have an open ventral furrow phenotype.

    The Df(3L)BK10 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    The Df(3L)BK10 mutation induces premature mitosis in cells that form the ventral furrow. Among Df(3L)BK10 embryos, there is a small fraction containing patches of higher nuclear density which appear to be due to an extra (14th) cleavage division prior to cellularization. The nuclei/cells that divide only 13 times are more advanced than the nuclei that go through an additional mitosis and enter gastrulation later.

    Heterozygosity for Df(3L)BK10 results in 0.4% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    Homozygous mutants embryos show a failure to form a ventral furrow. The mesoderm primordium is internalised late.

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    The larval cuticle of homozygotes is weak, as seen by frequent holes at random positions in the exoskeleton.

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    Midgut development of mutant embryos is wild type.

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Stocks (2)
    Notes on Origin
    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    "71C3;71E5" was stated as revision.

    Synonyms and Secondary IDs (6)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (39)