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General Information
D. melanogaster
Deficiency (3L) kohtalo
FlyBase ID
Feature type
Also Known As
Df(3L)kto2, Df(3L)JK18, Df(2R)kto2
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << kto << bk2 << fln

Genetic mapping information
Comments on Cytology

All limits from polytene analysis (FBrf0080459)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Fails to complement Df(3L)fln1 and Df(3L)VW3.

    NOT in combination with other aberrations

    Only the distal tip of the salivary gland turns in embryos homozygous for Df(3L)kto2 by stage 14.

    Df(3L)kto2 embryos show defects in tracheal cell migration.

    Dominantly enhances the KrIf-1/+ eye phenotype.

    No effect on the eye pigment phenotype of wT81.

    Homozygous lethal. Heterozygotes have longer locomotor rhythm periods than normal.

    Flies have a normal flight index.

    Does not rescue the lethal phenotype of three doses of Tpl+.

    Mutation changes the level of w expression in ph-plac+3 flies; eye colour is darker.

    Only 13% of neurons in Df(3L)kto2 flies have a transient K+ current.

    Stocks (3)
    Notes on Origin

    Kennison, 1987.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    The Df(3L)kto2 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    Synonyms and Secondary IDs (9)
    References (63)