FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3R)by10
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General Information
Symbol
Df(3R)by10
Species
D. melanogaster
Name
Deficiency (3R) blistery
FlyBase ID
FBab0002713
Feature type
chromosomal_deletion
Also Known As
Df(3R)by10
Computed Breakpoints include

85D8;85E10-85E13

Features within 85D8--85E13
Genomic Maps
Sequence coordinates
3R:9,468,786..9,495,877 (Df(3R)by10:bk1)
(Yamamoto et al., 2009.12.23)
3R:9,797,925..9,803,717 (Df(3R)by10:bk2)
(Yamamoto et al., 2009.12.23)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Kemphues et al., 1980)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Salzberg et al., 1997, Bhadra and Birchler, 1996, Craig and Brink, 1996, Duffy et al., 1996, Schnorr and Berg, 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Simon et al., 1991, Reuter et al., 1986, Kemphues et al., 1983, Kemphues et al., 1980)
Breakpoints

85D7--9;[]

(Kemphues et al., 1980)

85D8-85D12;85E7-85F1

(Li et al., 1997, Salzberg et al., 1997, Bhadra and Birchler, 1996, Craig and Brink, 1996, Duffy et al., 1996, Pauli et al., 1995, Reuter et al., 1986, Kemphues et al., 1983)

85D8-85D11;85E10-85E13

(Schnorr and Berg, 1996, Simon et al., 1991)

85D8-85D12;84E7-84F1

(Harbecke and Lengyel, 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(3)05430 << bk1 << sic << MtnA << bk2 << MED6

Genetic mapping information
Comments
Comments on Cytology

The left Df(3R)by10 breakpoint lies within CG16779 or CG8147 or in the region between them, and lies in the range 3R:5294508..5321599 (R5) (predicted cytology: 85D17-18).

(Yamamoto et al., 2009.12.23)

The right Df(3R)by10 breakpoint lies within CG9467 or CG8526 or in the region between them, and lies in the range 3R: 5623647..5629439 (R5) (predicted cytology: 85E9).

(Yamamoto et al., 2009.12.23)

Left limit of break 1 from polytene analysis (FBrf0045055) Right limit of break 1 from inclusion of Aats-trp (FBrf0067338) Left limit of break 2 from inclusion of MtnA (FBrf0044456) Right limit of break 2 from polytene analysis (FBrf0053392)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
by
(Kemphues et al., 1980)
dc
(Craig and Brink, 1996)
dmt
(Salzberg et al., 1994)
eca
(Bartoszewski et al., 2004)
hyd
(Seshaiah et al., 2001, Mansfield et al., 1994)
knk
(Tearle and Nusslein-Volhard, 1987)
l(3)85Da
(Seshaiah et al., 2001)
l(3)85Da-2
(Seshaiah et al., 2001)
l(3)85Db
(Seshaiah et al., 2001)
l(3)85Dc
(Seshaiah et al., 2001)
l(3)85Dd
(Seshaiah et al., 2001)
l(3)85De
(Seshaiah et al., 2001)
l(3)85Df
(Seshaiah et al., 2001)
l(3)85Dh
(Seshaiah et al., 2001)
l(3)85Di
(Seshaiah et al., 2001)
l(3)85Dj
(Seshaiah et al., 2001)
l(3)85Eb
(Seshaiah et al., 2001)
l(3)85Ec
(Seshaiah et al., 2001)
l(3)85Ed
(Seshaiah et al., 2001)
l(3)85Ee
(Seshaiah et al., 2001)
l(3)85Eh
(Seshaiah et al., 2001)
l(3)85Ei
(Seshaiah et al., 2001)
l(3)L4092
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
MED6
(Gim et al., 2001)
ms(3)85E
(Matthews, 1998.8.27)
ms(3)Z2203
(Ceprani et al., 2008)
MtnA
(Maroni et al., 1986)
ps
(Seshaiah et al., 2001)
pum
(BDGP Project Members, 1994-1999)
Ras85D
(Schnorr et al., 2001, Fischer et al., 1997, Schnorr and Berg, 1996, Begemann et al., 1995, Kramer et al., 1995, Kolodkin et al., 1994, Simon et al., 1991)
Scm
(Seshaiah et al., 2001, Harbecke and Lengyel, 1995, Tearle and Nusslein-Volhard, 1987, Jurgens, 1985)
sd-10
(Babcock et al., 2003)
Sec23
(Giesen, 2001.1.24)
sic
(Tearle and Nusslein-Volhard, 1987)
topi
(Perezgasga et al., 2004)
TrpRS
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
tws
(BDGP Project Members, 1994-1999)
vacu
(Palladino et al., 2002)
αTub85E
(Seshaiah et al., 2001)
βTub85D
(Jattani et al., 2009)
Partially deleted / disrupted
l(3)SG38
(Bloomington Drosophila Stock Center, 2009.9.22)
Molecular Data
Completely deleted
mRpL47
(Marygold et al., 2007)
RpS29
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (90)
Phenotypic Data
In combination with other aberrations

Complements: Df(3R)swp2MICAL. Complements: Df(3R)swp4. Complements: Df(3R)swp7. Complements: Df(3R)swp11. Complements: Df(3R)swp38.

(Terman et al., 2002)

Does not show a dose-sensitive interaction with Df(3R)Ubx109.

(Boube et al., 1997)
NOT in combination with other aberrations

In homozygous Df(3R)by10 embryos, the salivary gland distal tip does not initiate the posterior turn at stage 12 in contrast to wild-type, and the salivary gland fails to migrate posteriorly by stage 14.

(Jattani et al., 2009)

Flies heterozygous for the deletion show a Minute bristle phenotype.

(Marygold et al., 2007)

The Df(3R)by10 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3R)by10 results in 0.7% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

(Harris et al., 2003)

Homozygous embryos have abnormal gut morphology.

(Merabet et al., 2002)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.

(Burnette et al., 1999)

No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpphr4.

(Nicholls and Gelbart, 1998)

Shows a dose-sensitive interaction with pbhs.PB.

(Boube et al., 1997)

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

(Duffy et al., 1996)

Suppressor of the dosage dependent (two or more copies of P{sev-svp1} or P{sev-svp2}) transformation of cone cells into R7 photoreceptors and at a lower frequency R7 cells into outer photoreceptors.

(Begemann et al., 1995)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Homozygous embryos are very abnormal compared to wild-type.

(Harbecke and Lengyel, 1995)

Suppression of the rough eye phenotype (formation of extra R7 cells) caused by P{sev-svp2} and enhancement of the P{ro-svp1} rough eye phenotype (loss of one or more outer photoreceptors from many of the ommatidia).

(Kramer et al., 1995)

Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.

(Pauli et al., 1995)

In a sev6/Y, SosJC2/+ background, the percentage of ommatidia with R7 cells drops, in heterozygotes, from the 16% of sev6/Y, SosJC2/+ to 0%.

(Kolodkin et al., 1994)

Embryonic lethal.

(Mansfield et al., 1994)

Poor gut differentiation.

(Smith et al., 1993)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

knk has been found to complement Df(3R)by10, contradicting earlier work (FBrf0041709).

(Ostrowski et al., 2002)
Synonyms and Secondary IDs (6)
References (85)