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General Information
Symbol
Df(3R)by10
Species
D. melanogaster
Name
Deficiency (3R) blistery
FlyBase ID
FBab0002713
Feature type
Also Known As
Df(3R)by10
Computed Breakpoints include
Sequence coordinates
3R:9,468,786..9,495,877 (Df(3R)by10:bk1)
3R:9,797,925..9,803,717 (Df(3R)by10:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(3)05430 << bk1 << sic << MtnA << bk2 << MED6

Genetic mapping information
Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

Comments on Cytology

The left Df(3R)by10 breakpoint lies within CG16779 or CG8147 or in the region between them, and lies in the range 3R:5294508..5321599 (R5) (predicted cytology: 85D17-18).

The right Df(3R)by10 breakpoint lies within CG9467 or CG8526 or in the region between them, and lies in the range 3R: 5623647..5629439 (R5) (predicted cytology: 85E9).

Left limit of break 1 from polytene analysis (FBrf0045055) Right limit of break 1 from inclusion of Aats-trp (FBrf0067338) Left limit of break 2 from inclusion of MtnA (FBrf0044456) Right limit of break 2 from polytene analysis (FBrf0053392)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Complements: Df(3R)swp2MICAL. Complements: Df(3R)swp4. Complements: Df(3R)swp7. Complements: Df(3R)swp11. Complements: Df(3R)swp38.

Does not show a dose-sensitive interaction with Df(3R)Ubx109.

NOT in combination with other aberrations

In homozygous Df(3R)by10 embryos, the salivary gland distal tip does not initiate the posterior turn at stage 12 in contrast to wild-type, and the salivary gland fails to migrate posteriorly by stage 14.

Flies heterozygous for the deletion show a Minute bristle phenotype.

The Df(3R)by10 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

Heterozygosity for Df(3R)by10 results in 0.7% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

Homozygous embryos have abnormal gut morphology.

Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.

No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

Shows no maternal enhancement of dpphr4.

Shows a dose-sensitive interaction with pbhs.PB.

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

Suppressor of the dosage dependent (two or more copies of P{sev-svp1} or P{sev-svp2}) transformation of cone cells into R7 photoreceptors and at a lower frequency R7 cells into outer photoreceptors.

Deficient embryos show an uninterpretable mutant midgut phenotype.

Homozygous embryos are very abnormal compared to wild-type.

Suppression of the rough eye phenotype (formation of extra R7 cells) caused by P{sev-svp2} and enhancement of the P{ro-svp1} rough eye phenotype (loss of one or more outer photoreceptors from many of the ommatidia).

Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.

In a sev6/Y, SosJC2/+ background, the percentage of ommatidia with R7 cells drops, in heterozygotes, from the 16% of sev6/Y, SosJC2/+ to 0%.

Embryonic lethal.

Poor gut differentiation.

Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

knk has been found to complement Df(3R)by10, contradicting earlier work (FBrf0041709).

Synonyms and Secondary IDs (6)
References (85)