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General Information
Symbol
Dp(1;1)Co
Species
D. melanogaster
Name
Duplication (1;1) Confluens
FlyBase ID
FBab0003047
Feature type
Computed Breakpoints include

3C4-3C5;3D6-3E1

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << N << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (citation unavailable)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    When males with Dp(1;1)Co are crossed with T(1;2)scS2 females, and somatic clones are induced (in the wing disc) with a FRT site at 18A, clones with cells containing 4 copies of dm (2 endogenous and 2 from the tandem duplication in Dp(1;1)Co) and heterozygous for RpL19 (due to missing one copy of RpL19 on Ts(1Lt;2Lt)scS2). These clones are unable to out-compete surrounding cells and are eliminated.

    Single cells from Dp(1;1)Co/Dp(1;1)Co ; Dp(1;2)51b/Dp(1;2)51b embryos transplanted into the ventral neurogenic region of wild-type host embryos give rise to a reduced proportion of neural cells compared to wild-type controls.

    Df(1)N55l/Dp(1;1)Co flies are wild-type except for a slight delta effect in approximately 50% of the flies.

    NOT in combination with other aberrations

    When somatic clones are made in the wing disc that are homozygous for Dp(1;1)Co (thus 4 copies of dm - 4xdmyc, two endogenous and two on the duplication) in a wild-type background, out-compete sibling clones with just the two wild-type copies of dm, and are several times larger. When similar clones are made in the adult, the 4xdmyc clones are also several times larger than the surrounding wild-type tissue. When 4xdmyc and 2xdmyc clones are made in wing discs that express pucUAS.cMa or BacA\p35UAS.cHa (driven by Scer\GAL4hh-Gal4) in the posterior compartment, 2xdmyc clones grow significantly more slowly than 4xdmyc clones in the Anterior (control) compartment. This effect is lessened in the posterior compartment. The 4xdmyc clones also grow less well in the posterior compartment.

    No significant effect on the scaMSKF mutant phenotype.

    Duplication wing vein defects. Defects are slightly increased by heterozygosity for vg and homozygosity for sca and suppressed by extra copies of vg+ and sca+.

    Veins irregularly thickened, especially toward tips, which are usually deltas and fused broadly to marginal vein. Stronger expression in males than in females. Dp(1;1)Co/Df(1)N-8 wild type except for slightly thicker L3 vein. Dp(1;1)Co/Ax like Ax/+.

    Stocks (2)
    Notes on Origin
    Discoverer

    Gottschewski, March 1934.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Reversion to wild type occurs in Dp(1;1)Co/Dp(1;1)Co by unequal crossing over.

    Synonyms and Secondary IDs (7)
    Reported As
    Symbol Synonym
    Co
    Dp (1;1) Co
    Dp(1;1)Co
    NCo-1
    Name Synonyms
    Duplication (1;1) Confluens
    Secondary FlyBase IDs
    • FBal0012862
    References (15)