FlyBase Aberration Report: Dmel\In(1)w[m4h]

General Information

Symbol

In(1)w^m4h

Species

D. melanogaster

Name

FlyBase ID

FBab0004265

Feature type

chromosomal_inversion

Also Known As

w^m4h, In(1)wm4h

Computed Breakpoints include

3C2--3;[]

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

In(1)w^m4

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Reuter et al., 1985)

Mutagen

spontaneous

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Reuter et al., 1985)

Class of aberration (relative to wild type)

chromosomal_inversion

Class of aberration (relative to progenitor)

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

Comments on Cytology

Unchanged from progenitor.

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Reuter et al., 1985)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Reuter et al., 1985)

Myc

(Reuter et al., 1985)

(Laible et al., 1997)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

The position effect variegation (PEV) at the w locus seen in the In(1)w^m4h chromosome is suppressed if males are also carrying one of Df(Y)l-481, Df(Y)l-498, Df(Y)l-510 or Df(Y)l-473.

(Paredes and Maggert, 2009)

NOT in combination with other aberrations

Variegated w expression that can be suppressed by Su(var)2-1 mutations.

(Laible et al., 1997)

w variegation leads to clones of phenotypically wild-type cells in a mutant background. This phenotype is suppressed by crm^sa.

(Yamamoto et al., 1997)

The presence of a single copy of Mow mutation significantly increases the amount of pigment in both males and females, both Mow^EMS and Mow^gamma suppress position effect variegation.

(Bhadra and Birchler, 1996)

Mottled eye phenotype.

(Henchoz et al., 1996)

Males exhibit a mottled eye phenotype. Variegation is enhanced by E2f1¹⁶⁴.

(Seum et al., 1996)

Variegation at the w locus caused by In(1)w^m4h is enhanced by Su(var)3-7^hs.PCa or Su(var)3-7^hs.PCb, even in the absence of heat shock.

(Cleard et al., 1995)

Position effect variegation of w is moderately suppressed by mutations of Rm62. Suppression by allele of Rm62 is additive, heteroallelic escapers are more strongly suppressed than heterozygotes.

(Csink et al., 1994)

Males display a variegated eye phenotype, red spots are clones of cells expressing the w gene and white spots are w inactivation due to heterochromatinisation. Males also heterozygous for Trl^13C the eye colour is almost white, indicated a more frequent inactivation of the w gene.

(Farkas et al., 1994)

Intermediate variegating line. Eyes show strong white mottling with red patches on a white background.

(Reuter et al., 1985)

eyes strongly variegated

Stocks (35)

Bloomington

76618

In(1)w^m4h, y¹ ac¹

6235

In(1)w^m4h; Su(var)2-10²/CyO

6883

In(1)w^m4h; Su(var)2-4⁰¹ pie⁵⁴/CyO

Kyoto

101141

In(1)w^m4h / Df(YS)bb^-

101652

In(1)w^m4h ; e¹ by¹

101657

In(1)w^m4h ; sr¹ gl¹

101822

In(1)w^m4h ; Su(var)205² / SM1

103315

In(1)w^m4h ; Su(var)3-10² / TM3

101655

In(1)w^m4h ; Pri¹ Dr¹ / TM3

103330

In(1)w^m4h, y¹ ; Df(2L)TE29Aa-11 / CyO

102018

In(1)w^m4h ; CyO / sna^Sco ; ry⁵⁰⁶

101654

In(1)w^m4h ; Ki¹ rn^roe-1 p^p

More stocks available...

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

This is simply a line of In(1)w^m4 selected for strong variegation of w.

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

In(1)W^m4h

(Zhao et al., 2008)

In(1)w ^m4h

(Kavi and Birchler, 2009)

In(1)w^m4h

(Faragó et al., 2021, Barish et al., 2020, Yang et al., 2019, Guida et al., 2016, Gandhi et al., 2015, Ito et al., 2012, Di Stefano et al., 2011, Gurudatta et al., 2010, Buszczak et al., 2009, Fagegaltier et al., 2009, Bassett et al., 2008, Grau et al., 2008, Hanai et al., 2008, Sweeney et al., 2008, Demakova et al., 2007, Seum et al., 2007, Möller et al., 2005, Czermin et al., 2001)

In(1)w^mottled4h

(Qi et al., 2006)

In(1)wm4h

(Reo et al., 2010, Lloret-Llinares et al., 2008)

ln(1)w^M4H

(Beckstead et al., 2005)

Name Synonyms

white-mottled4h

(Kavi and Birchler, 2009)

Secondary FlyBase IDs

FBal0018269

References (91)

Report Sections

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