FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\In(3LR)234
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General Information
Symbol
In(3LR)234
Species
D. melanogaster
Name
FlyBase ID
FBab0005359
Feature type
chromosomal_inversion
Also Known As
dumb1
Computed Breakpoints include

67D6-67D8;88A10-88B1

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Craymer, 1984)
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Coyne et al., 1993, Craymer, 1984)
Breakpoints

67D;88A-88B

(Coyne et al., 1993)

67D6-67D8;88A10-88B1

(Craymer, 1984)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0063387)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Dop1R1
(Kim et al., 2007)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    In(3LR)234/Df(3R)ED5634 flies show reduced ethanol-induced hyperactivity.

    (Kong et al., 2010)
    NOT in combination with other aberrations

    In(3LR)234 homozygous adults show an apparently normal sensitivity to ethanol as compared to controls: they shown an apparently normal time until sedation and a normal tolerance development following daily exposures; they also show normal ethanol-induced disinhibition, as shown by the increasing frequency of inter-male courtship upon continual exposure.

    (Aranda et al., 2017)

    In(3LR)234 mutants exhibit significantly impaired water learning.

    (Lin et al., 2014)

    In(3LR)234 mutant larvae show a significantly reduced performance in aversive and appetitive olfactory learning (using amylacetate (AM) and benzaldehyde (BA)) compared to controls. Perception of AM, BA and sugar are similar to wild type, but salt perception is significantly reduced.

    (Selcho et al., 2009)

    In(3LR)234/Df(3R)su(Hw)7 and In(3LR)234/In(3LR)234 adults fail to learn to avoid specific odors after conditioning by concurrent shock and odor exposure.

    (Kim et al., 2007)

    Homozygous viable, fertile and phenotypically wild type.

    (Craymer, 1984)

    Transvects Cbx Ubx/+. homozygous viable homozygous fertile homozygous phenotypically wild type

    Stocks (1)
    Notes on Origin
    Discoverer

    S. Ou.

    (Craymer, 1984)

    Ou.

     

    Selected as: detectable transvection of Ubx/+.

    (Craymer, 1984)

    from Canton-S

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    References (15)