FB2026_03 , released September 17, 2026
Aberration: Dmel\T(2;3)Mpe
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General Information
Symbol
T(2;3)Mpe
Species
D. melanogaster
Name
Translocation (2;3) Monoplane
FlyBase ID
FBab0007686
Feature type
chromosomal_translocation
Computed Cytological Breakpoints (relative to progenitor)

35B2;86C1-86C2

Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Hughes and Shelton, 1980)
Class of aberration (relative to wild type)
chromosomal_translocation
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_translocation
(McNabb et al., 1996, Roote et al., 1996, Gubb et al., 1990, Ashburner et al., 1981)
Cytological Breakpoints (relative to progenitor)

35B2-35B3;86C1-86C2

(McNabb et al., 1996, Ashburner et al., 1981)

35B2-35B3;86C

(Gubb et al., 1990)

35B1-35B2;86C1-86C2

(Roote et al., 1996, Ashburner et al., 1990)
Causes alleles
Mpe1
(Hughes and Shelton, 1980)
ospMpe
(Ashburner et al., 1999.10.12)
Carries alleles
Transposon Insertions
Formalized genetic data

osp << bk1 << Adh

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Chia et al., 1985)

35B2-3 breakpoint at -103 to -106.5 bp in the molecular map of the wild-type noc-Adh region (McGill et al., 1988) (coordinate 0 on EcoR1 restriction site 1321 bp to the left of the start of transcription of the larval Adh transcript, '+' values to the right, '-' values to the left).

Comments on Cytology

Since osp is very near the 2L breakpoint of this translocation the Mpe phenotype may be due to a dominant osp allele.

(Ashburner et al., 1981)

Left limit of break 1 from polytene analysis (FBrf0036112) Right limit of break 1 from polytene analysis (FBrf0051973) Limits of break 2 from polytene analysis (FBrf0036112)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
osp
(McNabb et al., 1996)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Weakly suppresses the zeste phenotype in a z1 w11E4; Tp(1;2)TE35B homologue.

    (Gubb et al., 1990)

    T(2;3)Mpe/Df(3R)cu40 lethal T(2;3)Mpe/Df(3R)by77 lethal

    NOT in combination with other aberrations

    Chromosome acts as a weak trans-suppressor of a physical interaction between tandemly duplicated copies of w+, an interaction that is required for the suppression of genes by z1.

    (Gubb et al., 1990)

    Associated with dominant Mpe phenotype and recessive osp allele. Also shows a dominant leg phenotype (thickening of the tibial-tarsal joint of the metathoracic leg). Phenotypes of leg and outstretched-wing associated with 2P3D element of the translocation. homozygous lethal Heterozygotes reduced in viability (Hughes and Shelton, 1980) Heterozygotes reduced in fertility (Hughes and Shelton, 1980) T(2;3)Mpe heterozygous with a deletion of the entire noc region is noc+ (McGill et al., 1988).

    Stocks (0)
    Notes on Origin
    Discoverer

    Shelton.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    T(2;3)Mpe
    T(2;3)Mpl
    Name Synonyms
    Translocation (2;3) Monoplane
    Secondary FlyBase IDs
      References (12)