FB2021_06, released December 14, 2021

Aberration: Dmel\Tp(1;2)TE35B

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General Information
Symbol
Tp(1;2)TE35B
Species
D. melanogaster
Name
FlyBase ID
FBab0009172
Feature type
interchromosomal_transposition
Also Known As
TE146(Z), TE146
Computed Breakpoints include

3C;3C;35B2

Sequence coordinates
2L:14,501,859..14,502,617 [+] (Tp(1;2)TE35B:bk3)
(Chia et al., 1985)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Tp(1;2)TE60Ba
(Ashburner et al., 1981)
Mutagen
spontaneous
Class of aberration (relative to wild type)
interchromosomal_transposition
Class of aberration (relative to progenitor)
chromosomal_transposition
(Roote, 2004.6.24)
Breakpoints

[];[];35B2--3

(Ashburner et al., 1981)

3C;3C;35B2

(Roote, 2004.6.24)
Causes alleles
nocTE35B
(Ashburner et al., 1999, Ashburner et al., 1999.10.12, Davis et al., 1997, Lovering et al., 1991, Gubb et al., 1986, Ashburner et al., 1981)
Carries alleles
Transposon Insertions
Formalized genetic data

bk3 hits noc

Genetic mapping information

Genetic location of w and/or rst : 2-50.0 +/- 0.2.

Comments

FBw<up>+ rst+ w+ rst+</up>; 6 polytene bands

Comments on Cytology

Carries a tandem repeat of z+ and rst+.

(Gubb et al., 1997)

Breakpoints molecularly mapped.

(Lovering et al., 1991)

Breakpoint in 2L is just proximal to 35B1-35B2. Comprised of 6 polytene bands.

(Gubb et al., 1986)

Insertion of at least 6 polytene chromosome bands just proximal to 35B1-35B2.

(Gubb et al., 1985)

Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 2 from polytene analysis (citation unavailable) Left limit of break 3 from polytene analysis (FBrf0036112) Right limit of break 3 from complementation mapping against noc (FBrf0036112)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
noc
(Davis et al., 1997, Lovering et al., 1991, Harden and Ashburner, 1990, Gubb et al., 1986, Gubb et al., 1985, Ashburner et al., 1981)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    z1 w11E4 ; Tp(1;2)TE35B/Tp(1;2)TE35BC, z1 w11E4 ; Tp(1;2)TE35B-SR22/Tp(1;2)TE35B and z1 w11E4 ; In(2LR)TE35B-4/Tp(1;2)TE35B flies have zeste eyes. z1 w11E4 ; Tp(1;2)TE35B-SZ1/Tp(1;2)TE35B, z1 w11E4 ; Tp(1;2)TE35B-GR12/Tp(1;2)TE35B and z1 w11E4 ; Tp(1;2)TE35B-GR2/Tp(1;2)TE35B flies have zeste eyes with a crescent of red ommatidia along the posterior edge. z1 w11E4 ; Tp(1;2)TE35B-GR20/Tp(1;2)TE35B flies have dark zeste eyes. z1 w11E4 ; Tp(1;2)TE35B-GR17/Tp(1;2)TE35B and z1 w11E4 ; Tp(1;2)TE35B-GR9/Tp(1;2)TE35B flies have red eyes.

    (Gubb et al., 1997)

    Zeste eye colour in heterozygous combination with Tp(1;2)TE35BC in a z1 w11E4 background. Red eye colour in heterozygous combination with Tp(1;2)TE34Cc or Tp(1;3)TE89Da in a z1 w11E4 background. Viable when hemizygous with noc- deletions.

    (Gubb et al., 1986)
    NOT in combination with other aberrations

    Tp(1;2)TE35B/Tp(1;2)TE35B and z1 w11E4 ; Tp(1;2)TE35B/Tp(1;2)TE35B flies have zeste eyes.

    (Gubb et al., 1997)

    Homozygous viable. Zeste eye colour when heterozygous or homozygous in a z1 w11E4 background.

    (Gubb et al., 1986)

    Homozygous viable. Heterozygous males have an almost wild-type eye colour, but the eyes of heterozygous females are less red, with a purple tint.

    (Gubb et al., 1985)

    Eye color on a w- background genotype: red; suppressed by z1 homozygous viable

    Stocks (0)
    Notes on Origin
    Discoverer

    Ising.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
    Other Comments
     

    Contains a tandem repeat of the w+ and rst+ genes bounded by FB elements. There are also NOF sequences within the TE. Both copies of rst appear to have a NEB element inserted at a similar site. The copies of w probably carry a small (approximately 250bp) insertion, which is probably a copia LTR. The junctions between FB and non-FB sequences within Tp(1;2)TE35B have been molecularly mapped.

    (Lovering et al., 1991)

    Carries duplicate copies of w+ and rst+. This rearrangement is associated with four FB elements, one of which also includes NOF sequences.

    (Harden and Ashburner, 1990)

    Carries two copies of w+ and rst+ in tandem (distal-proximal order: w+ rst+ w+ rst+).

    (Gubb et al., 1986)

    Carries a duplication of both the w and rst genes.

    (Gubb et al., 1985)
    Synonyms and Secondary IDs (6)
    References (21)