FlyBase Aberration Report: Dmel\Tp(1;2)r[+]75c

General Information

Symbol

Tp(1;2)r⁺75c

Species

D. melanogaster

Name

Transposition (1;2) rudimentary-wild type

FlyBase ID

FBab0009473

Feature type

interchromosomal_transposition

Also Known As

T(1;2)r^+75c, Tp(1;2)r^+75c

Computed Breakpoints include

14B13;15A9;35D-35E

Features within 14B13--15A9

Sequence coordinates

X:16,352,503..16,354,240 [-] (Tp(1;2)r[+]75c:bk1)

(Thackeray et al., 1998, Jones and Rubin, 1990)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

interchromosomal_transposition

Class of aberration (relative to progenitor)

uninverted_interchromosomal_transposition

(Simmons et al., 1984, Craymer and Roy, 1980)

unoriented_interchromosomal_transposition

(Mason et al., 1981)

Breakpoints

14B13;15A9;[]

(Simmons et al., 1984, Mason et al., 1981, Lim, 1979)

14B13;15A9;35D-35E

(Stern et al., 1990, Craymer and Roy, 1980)

14C1-14C2;15A9

(Kulkarni et al., 1988)

14C1--14C2;15A9;[]

(Banga et al., 1995)

Causes alleles

sl³

(Thackeray et al., 1998, Schalet, 1986)

Carries alleles

Transposon Insertions

Formalized genetic data

bss << bk1 << sl << Axs << bk2 << l(1)ESHS50

Genetic mapping information

Comments

Breakpoint 1 was linked to a BamHI-PstI restriction fragment. The position of the restriction fragment on the reference sequence was inferred by a FlyBase curator.

(Thackeray et al., 1998)

Comments on Cytology

15A9 break revised by H. Steller.

(Banga et al., 1995)

Limits of break 1 from polytene analysis (FBrf0033204) Limits of break 2 from polytene analysis (FBrf0033204) Limits of break 3 from polytene analysis (FBrf0052687)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

para

(Song and Tanouye, 2007)

Rok

(Winter et al., 2001)

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

In Tp(1;2)r⁺75c aCC/RP2 neurons, the magnitude of the persistent component of voltage-gated Na⁺ current is significantly increased relative to controls, while the transient component is significantly different.

(Mee et al., 2004)

Mutants exhibit a 'pebbly' eye.

(Craymer and Roy, 1980)

'Pebbly' eyes (Craymer and Roy, 1980) is the result of a sl mutation associated with the distal X breakpoint at 14B1-3 (Schalet, 1986, Mutat. Res. 163: 115-44).

Stocks (2)

Bloomington

3217

C(1)M4, y²; Tp(1;2)r⁺75c, sl³/CyO

Kyoto

106924

Tp(1;2)r⁺75c, sl³/CyO; C(1)M4, y²

Notes on Origin

Discoverer

Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components