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General Information
D. melanogaster
FlyBase ID
Also Known As
Computed Breakpoints include


Sequence coordinates
2L:14,492,811..14,496,471 [+] (Tp(2;2)A446:bk1)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

2Lt - 35B1 | 36C2 - 49B1 | 35F2 - 36C1 | 49B3 - 2Rt

Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)






Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << noc << mol << bk2 << twe

Genetic mapping information

Lesion within noc.

Comments on Cytology


35B1-35B2;35E6;35F1-35F2;36C1-36C2;49B1-49B3 2Lt - 35B1 | 35E6 - 35F1 | 36C2 - 49B3 | (35F2 - 36C1) | 49B3 - 2Rt


Other breakpoints not reported.

Limits of break 1 from polytene analysis (FBrf0038047) Limits of break 2 from polytene analysis (FBrf0043115) Limits of break 3 from polytene analysis (FBrf0043115) Limits of break 4 from polytene analysis (FBrf0043115) Four-break event separable into a deficient and a duplicated component.

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    The net plus-end (phase II) transport of lipid droplets along microtubules is disrupted in Df(2L)dp-79b/Tp(2;2)A446 embryos, resulting in the apical accumulation of droplets in the embryo.

    NOT in combination with other aberrations

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Chromosome has no effect on the physical interaction between tandemly duplicated copies of w+ and z1, despite having breakpoints within the critical region.

    Very weak, sterile, small fly and dominant wavy wing phenotype.

    heterozygous semi-lethal escapers are sterile and have a wavy-wing and small-fly phenotype.

    Stocks (0)
    Notes on Origin



    selected as ADH null on 1-penten-3-ol.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    Aberration has no effect on z but has breakpoints within the z critical region.

    Note that Df(2L)A446 is not an aneuploid recombinant between Tp(2;2)A446 and a wild-type sequence, but merely a synonym for Tp(2;2)A446, since Tp(2;2)A446 is deficient in region 35B-35E. A deficient recombinant which would be deleted for 35B-36C, would probably be dominant lethal.

    Synonyms and Secondary IDs (3)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
    • FBab0009751
    References (23)