FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(2L)slp-Δ34B
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General Information
Symbol
Df(2L)slp-Δ34B
Species
D. melanogaster
Name
FlyBase ID
FBab0022161
Feature type
chromosomal_deletion
Also Known As
slpΔ34b, Δ34B, slpΔ34B
Computed Breakpoints include

[24D1];[>25C1]

Features within 24D1--25C1
Genomic Maps
Sequence coordinates
2L:3,824,969..3,825,807 [+] (Df(2L)slp-Delta34B:bk1)
2L:3,837,076..3,839,497 [+] (Df(2L)slp-Delta34B:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
In(2LR)O
(Cadigan et al., 1994)
Mutagen
Delta2-3 transposase
(Cadigan et al., 1994, Cadigan et al., 1994, Grossniklaus et al., 1992)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Grossniklaus et al., 1992)
Breakpoints

[];[]

(Grossniklaus et al., 1992)
Causes alleles
slp1Δ34B
(Lee and Frasch, 2000, Riechmann et al., 1997, Cadigan et al., 1994, Cadigan et al., 1994, Grossniklaus et al., 1992)
slp2Δ34B
(Lee and Frasch, 2000, Riechmann et al., 1997, Cadigan et al., 1994, Cadigan et al., 1994, Grossniklaus et al., 1992)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits slp1 << l(2)25Cd << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from non-inclusion of slp1 (FBrf0056100) Right limit of break 1 from inclusion of slp1 (FBrf0056100) Left limit of break 2 from inclusion of l(2)25Cd (FBrf0096157)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
l(2)25Cd
(Riechmann et al., 1997)
slp1
(Riechmann et al., 1997, Cadigan et al., 1994, Cadigan et al., 1994)
slp2
(Cadigan et al., 1994, Cadigan et al., 1994)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (2)
Phenotypic Data
In combination with other aberrations

Df(2L)slpS37A/Df(2L)slp-Δ34B embryos have fused denticle belts.

(Sato and Tomlinson, 2007)
NOT in combination with other aberrations

NB4-2 is not formed in 53% of hemisegments in mutant embryos. The RP2 lineage is missing; embryos lack the eve-positive GMC-1 cell and its progeny, RP2 and RP2-sib. The RP2 lineage phenotype is unaffected if the embryos are also carrying gsbunspecified or are carrying enunspecified and invunspecified.

(Bhat et al., 2000)

Embryonic lethal. Homozygotes display fusion of segments and lack of naked cuticle. Transheterozygotes with slp1Δ46G display a weaker phenotype and transheterozygotes with Df(2L)ed1 resemble the homozygote. One copy of the construct P{HS-slp1} can reduce the segmentation defect, some of the naked cuticle is replaced by extra denticles, and rescue transheterozygotes with slp1Δ46G to adulthood.

(Cadigan et al., 1994)

Embryonic lethal: head lobes fail to involute.

(Grossniklaus et al., 1992)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (11)
References (23)