FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)cnn
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General Information
Symbol
Df(2R)cnn
Species
D. melanogaster
Name
FlyBase ID
FBab0024394
Feature type
chromosomal_deletion
Computed Breakpoints include

50A2-50A6;50A15-50B2

Features within 50A2--50B2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{wF}1
(Heuer et al., 1995)
Mutagen
X ray
(Heuer et al., 1995)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Heuer et al., 1995)
Breakpoints

49F15;50A15-50B2

(Heuer et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << cnn << drk << bk2 << fas

Genetic mapping information
Comments
Comments on Cytology

Removes all of 50A and may delete some of the material from the 50B1-50B2 doublet.

(Heuer et al., 1995)

Right limit of break 1 from inclusion of cnn (FBrf0087566) Limits of break 2 from polytene analysis (FBrf0084021)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
cnn
(Megraw et al., 2002, Li and Kaufman, 1996)
drk
(Heuer et al., 1995)
wst
(Ohsako and Yamamoto, 2011)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Fails to complement Df(2R)vg-B, complements Df(2R)vg135.

    (Heuer et al., 1995)
    NOT in combination with other aberrations

    Homozygotes exhibit mitotic and midgut defects. Females with germline clones lay morphologically normal eggs for 5-6 days then stop laying. Older females exhibit discontinuity in the production of late stage egg chambers and nurse cell degeneration. Among the embryos produced from cnn- oocytes three classes can be defined: early arrest of nuclear division, completion of early nuclear division before undergoing necrosis and some hatch and develop to viable adults.

    (Li and Kaufman, 1996)

    Homozygotes develop up to the end of embryogenesis but fail to hatch. Nervous system and gut show defects with respect to expression of molecular markers. The second midgut constriction fails to form. The finger-like projections of the gastric caeca also fail to extend.

    (Heuer et al., 1995)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2R)Cnn
    (Li et al., 1998)
    Df(2R)cnn
    (Eisman et al., 2015, Ohsako and Yamamoto, 2011, Eisman et al., 2009)
    Name Synonyms
    Secondary FlyBase IDs
      References (10)