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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include


Sequence coordinates
3L:12,514,419..12,514,419 (Df(3L)ED4486:bk1)
3L:13,032,485..13,032,485 (Df(3L)ED4486:bk2)
Member of large scale dataset(s)

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

Comments on Cytology

Confirmed by 3-step PCR confirmation as shown in Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)0508805088 and P{PZ}l(3)0692406924 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}RpS12s2783 and P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Df(3L)ED4486 mutant clones in sensory neurons in adult wing do not display any defects in injury-induced axon degeneration (following an axotomy, the severed axons are cleared away normally).

No cardiac or bristle phenotypes are observed in heterozygous Df(3L)ED4486 mutant females.

The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)ED4486 by stage 14.

Df(3L)ED4486 homozygous embryos have defects in head involution, dorsal closure..

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

Stocks (2)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments
Synonyms and Secondary IDs (6)
References (30)