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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include


Sequence coordinates
2R:24,257,897..24,257,897 (Df(2R)Exel6082:bk1)
2R:24,369,777..24,369,777 (Df(2R)Exel6082:bk2)
Member of large scale dataset(s)

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.

The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Df(2R)BSC603/Df(2R)Exel6082 transheterozygotes are viable but show a blistered wing phenotype; the indirect flight muscles are correctly specified but there are myofibril defects (low polymerized actin content), while the jump muscles appear normal.

NOT in combination with other aberrations

Homozygotes show lethality at late stages of embryogenesis. The body wall muscles develop correctly in the mutant embryos and attach to the epidermis as in wild type. The gut elongates and forms gut constrictions in the mutant embryos and the visceral muscles develop normally. Cardioblasts of the dorsal vessel and macrophages are shaped normally in the mutant embryos. At the end of embryogenesis the mutant embryos are able to move in the eggshell and can contract their muscles (although not as frequently or as vigorously as wild type), but they do not hatch.

Stocks (1)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)