FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)Exel7157
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General Information
Symbol
Df(2R)Exel7157
Species
D. melanogaster
Name
FlyBase ID
FBab0038052
Feature type
chromosomal_deletion
Computed Breakpoints include

[55E2-55E2];[55E10-55E10];

Features within 55E2--55E10
Genomic Maps
Sequence coordinates
2R:18,621,522..18,621,522 (Df(2R)Exel7157:bk1)
(Bloomington Drosophila Stock Center, 2008.8.7)
2R:18,730,771..18,730,771 (Df(2R)Exel7157:bk2)
(Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)
Dfs_Exelixis_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.

The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.

(Cook, 2012.9.12, Parks et al., 2004)
Nature of Aberration
Cytological Order
Progenitor
P{XP}Atg7d06996
(Parks et al., 2004)
PBac{RB}Hs3st-Ae00779
(Parks et al., 2004)
Mutagen
FLPase
(Parks et al., 2004)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Parks et al., 2004)
Breakpoints

55E2;55E11

(Parks et al., 2004)

55E2;55E10

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P+PBac{XP5.RB3}Exel7157
(Parks et al., 2004)
Formalized genetic data
Genetic mapping information
Comments

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

(Bloomington Drosophila Stock Center, 2008.8.7)
Comments on Cytology

Limits computationally determined from location of progenitor P insertion on genome sequence between P{EP}EP437 and P{PZ}l(2)0370903709

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
oho55DE
(Kahsai et al., 2016)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (26)
Phenotypic Data
In combination with other aberrations

Df(2R)edl-S0520/Df(2R)Exel7157 transheterozygotes show cardioblast patterning defects in the embryo, with very few ostial cardioblasts, as compared to controls.

(Schwarz et al., 2018)

Lethal in combination with Df(2R)BSC399.

(Kahsai et al., 2016)

Df(2R)Exel7157/Df(2R)Exel7158 results in semi-lethality. Those animals that do survive to adulthood have no obvious morphological abnormalities and their viability is not at all compromised for at least two weeks in the absence of lithium treatment. However, the mutant adults are susceptible to 50mM LiCl; their general activity is severely impaired within one day of treatment, followed by death within the next few days (median time to lethality is 2.3 days).

(Kasuya et al., 2009)

Inferred to overlap with: Df(2R)BSC339.

(Christensen and Cook, 2007.10.29)
NOT in combination with other aberrations
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (1)
References (12)