Open Close
General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include


Sequence coordinates
2R:18,621,522..18,621,522 (Df(2R)Exel7157:bk1)
2R:18,730,771..18,730,771 (Df(2R)Exel7157:bk2)
Member of large scale dataset(s)

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.

The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Formalized genetic data
Genetic mapping information

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

Comments on Cytology

Limits computationally determined from location of progenitor P insertion on genome sequence between P{EP}EP437 and P{PZ}l(2)0370903709

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations

Df(2R)edl-S0520/Df(2R)Exel7157 transheterozygotes show cardioblast patterning defects in the embryo, with very few ostial cardioblasts, as compared to controls.

Lethal in combination with Df(2R)BSC399.

Df(2R)Exel7157/Df(2R)Exel7158 results in semi-lethality. Those animals that do survive to adulthood have no obvious morphological abnormalities and their viability is not at all compromised for at least two weeks in the absence of lithium treatment. However, the mutant adults are susceptible to 50mM LiCl; their general activity is severely impaired within one day of treatment, followed by death within the next few days (median time to lethality is 2.3 days).

NOT in combination with other aberrations
Stocks (1)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)