FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)BSC273
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General Information
Symbol
Df(2R)BSC273
Species
D. melanogaster
Name
FlyBase ID
FBab0045040
Feature type
chromosomal_deletion
Also Known As
Dh31rDf
Computed Breakpoints include

[49F4-49F4];[50A13-50A13];

Features within 49F4--50A13
Genomic Maps
Sequence coordinates
2R:13,159,579..13,159,579 (Df(2R)BSC273:bk1)
(Bloomington Drosophila Stock Center, 2008.8.7)
2R:13,502,150..13,502,150 (Df(2R)BSC273:bk2)
(Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)
Dfs_BSC_set2

A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped.

(Cook et al., 2012)
Nature of Aberration
Cytological Order
Progenitor
PBac{RB}ND-MWFEe00771
(Christensen and Cook, 2007.3.22)
P{XP}d07887
(Christensen and Cook, 2007.3.22)
Mutagen
FLPase
(Christensen and Cook, 2007.3.22)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Christensen and Cook, 2007.3.22)
Breakpoints

49F4;50A13

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P+PBac{XP5.RB3}BSC273
(Christensen and Cook, 2007.3.22)
Formalized genetic data
Genetic mapping information
Comments

Breakpoint based on release 3 sequence coordinate from Thibault et al., 2004, Supplementary Table 2 (FBrf0174227) or 3 (FBrf0174228), converted to release 5 coordinate.

(Bloomington Drosophila Stock Center, 2008.8.7)

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

(Bloomington Drosophila Stock Center, 2008.8.7)
Comments on Cytology

Exelixis, Inc. determined the insertion site of P{XP}d07887 to be at Release 3 genomic coordinate 8566864 on chromosome arm 2R. This corresponds to 50A13 on the Release 3 and 4 genome maps. The predicted position of PBac{RB}Cap-Ge00771 on the Release 4 map is 49F4. Consequently, the cytological breakpoints of Df(2R)BSC273 are predicted to be 49F4;50A13.

(Christensen and Cook, 2007.3.22)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
cnn
(Christensen and Cook, 2007.3.22)
Dp
(Christensen and Cook, 2007.3.22)
l(2)49Fa
(Kahsai and Cook, 2018)
l(2)49Fg
(Kahsai and Cook, 2018)
Orc3
(Christensen and Cook, 2007.3.22)
seq
(Kahsai and Cook, 2018, Dean et al., 2013)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (78)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Df(2R)BSC273 heterozygotes show an apparently normal temperature preference profile and an apparently normal circadian behavior (i.e. proportion of rhythmicity and circadian period), as compared to wild-type controls.

(Goda et al., 2018)

Dominantly modifies the size of pupae relative to wild-type controls.

(Walker et al., 2013)
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The presence of P+PBac{XP5.RB3}BSC273 was verified using the PCR methods and primers described in FBrf0175003.

(Christensen and Cook, 2007.3.22)
Synonyms and Secondary IDs (4)
References (24)