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General Information
Symbol
Df(3L)Gr64ab
Species
D. melanogaster
Name
FlyBase ID
FBab0045247
Feature type
Also Known As
Gr64ab
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Imprecise excision of the progenitor insertion, resulting in a 3.1kb deletion which removes the entire Gr64a gene and removes 868bp at the 5' end of Gr64b.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutant flies show normal responses to both low salt (50mM NaCl) and high salt (500mM NaCl) in a two-way choice test.

    Df(3L)Gr64ab flies prefer fructose to sucrose, whereas wild-type flies prefer sucrose. In addition Df(3L)Gr64ab flies fail to show a bias in favor of the 5mM over 1mM sucrose, but retain the ability to select the 5mM over 2mM fructose. Thus, the behavioral response to sucrose, but not fructose, is defective in Df(3L)Gr64ab flies. Df(3L)Gr64ab flies exhibit a normal preference for 20mM arabinose over 2mM fructose. However, unlike wild-type, the Df(3L)Gr64ab mutant prefers fructose over either glucose or maltose. Also in contrast to wildtype, Df(3L)Gr64ab selects fructose rather than trehalose, which is surprising given that trehalose is the ligand that activates Tre. Df(3L)Gr64ab flies show a normal aversion to quinine and caffeine.

    The frequencies of action potentials induced by sucrose, glucose, maltose, and trehalose are dramatically reduced in Df(3L)Gr64ab flies.

    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (5)